Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.41 |
| ▸ | TUBB | P07437 | 2/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15920842 | 1.00 | MAPT (0.56) | MAPTNPSR1KMT2AKDM4EALDH1A1 | |
| SCHEMBL15920893 | 0.87 | KDM4E (0.46) | MAPTNPSR1KMT2AKDM4EALDH1A1 | |
| SCHEMBL15920891 | 0.87 | KDM4E (0.46) | MAPTNPSR1KMT2AKDM4EALDH1A1 | |
| SCHEMBL17280384 | 0.87 | ALOX5 (0.42) | MAPTNPSR1KMT2AKDM4EALDH1A1 | |
| SCHEMBL15920749 | 0.82 | ALDH1A1 (0.71) | MAPTNPSR1KMT2AKDM4EALDH1A1 | |
| SCHEMBL15932525 | 0.81 | KDM4E (0.65) | MAPTNPSR1KMT2AKDM4EALDH1A1 | |
| SCHEMBL15920734 | 0.80 | MAPT (0.47) | MAPTNPSR1KMT2AKDM4EALDH1A1 | |
| SCHEMBL15920731 | 0.80 | MAPT (0.47) | MAPTNPSR1KMT2AKDM4EALDH1A1 | |
| SCHEMBL17280382 | 0.78 | TUBB4A (0.39) | MAPTNPSR1KDM4EALDH1A1LMNA | |
| SCHEMBL18872117 | 0.76 | KDM4E (0.60) | MAPTNPSR1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9650355-B2 | Method for preparation of justicidin a derivatives of arylnaphthalene lignan structure | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2017-05-16 | — | — | US | claimed |
| WO-2014119892-A1 | METHOD FOR PREPARATION OF JUSTICIDIN A DERIVATIVES OF ARYLNAPHTHALENE LIGNAN STRUCTURE | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2014-08-07 | — | — | WO | claimed |
| US-9650355-B2 | Method for preparation of justicidin a derivatives of arylnaphthalene lignan structure | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2017-05-16 | — | — | US | disclosed |
| US-20150336938-A1 | METHOD FOR PREPARATION OF JUSTICIDIN A DERIVATIVES OF ARYLNAPHTHALENE LIGNAN STRUCTURE | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2015-11-26 | — | — | US | disclosed |
| WO-2014119892-A1 | METHOD FOR PREPARATION OF JUSTICIDIN A DERIVATIVES OF ARYLNAPHTHALENE LIGNAN STRUCTURE | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2014-08-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150336938-A1 | METHOD FOR PREPARATION OF JUSTICIDIN A DERIVATIVES OF ARYLNAPHTHALENE LIGNAN STRUCTURE | UGT1A8, NOTUM, MLN | MAPT 3028/4885NPSR1 3558/4885KMT2A 1345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.