Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHAT | P28329 | 4/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.42 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.42 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.42 |
| ▸ | GNG2 | P59768 | 5/20 | 0.41 |
| ▸ | GNB1 | P62873 | 5/20 | 0.41 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1592195 | 0.85 | PHLPP2 (0.46) | CHATUSP2APEX1PHLPP2ENPP3 | |
| SCHEMBL1592676 | 0.84 | PHLPP2 (0.62) | CHATUSP2APEX1PHLPP2ENPP3 | |
| SCHEMBL11119700 | 0.82 | TGM2 (0.41) | THRBPKMRORC | |
| SCHEMBL11119697 | 0.73 | GNG2 (0.70) | CHATPHLPP2ENPP3ENPP1GNG2 | |
| SCHEMBL2609744 | 0.72 | PHLPP2 (0.53) | PHLPP2GNG2GNB1CYP1A2HSD17B10 | |
| SCHEMBL28221208 | 0.72 | PHLPP2 (0.48) | CHATUSP2APEX1PHLPP2GNG2 | |
| SCHEMBL2817311 | 0.71 | THRB (0.68) | CYP1A2CYP2C19THRBPKMCYP2C9 | |
| SCHEMBL16977398 | 0.71 | GSTO1 (0.55) | LMNAGSTO1 | |
| SCHEMBL28322468 | 0.71 | P2RY2 (0.56) | CHATUSP2APEX1PHLPP2ENPP3 | |
| SCHEMBL28195405 | 0.70 | P2RY4 (0.51) | GNG2GNB1CYP1A2MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110092659-A1 | Improved Method For Making Tinted Polymers | COGNIS IP MANAGEMENT GMBH (DE) | 2011-04-21 | — | — | US | disclosed |