Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | BLM | P54132 | 2/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.56 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.54 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | GMNN | O75496 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL109158 | 0.86 | MAPT (0.73) | MAPTTRPV1HSD17B10MEN1KMT2A | |
| SCHEMBL107219 | 0.85 | MAPT (0.71) | MAPTTRPV1HSD17B10MEN1KMT2A | |
| SCHEMBL26268646 | 0.84 | KDM4E (0.54) | MAPTTRPV1HPGDKDM4EALDH1A1 | |
| SCHEMBL18090283 | 0.82 | MAPT (0.49) | MAPTTRPV1HSD17B10MEN1KMT2A | |
| SCHEMBL9476748 | 0.81 | TRPV1 (0.70) | MAPTTRPV1HSD17B10MEN1KMT2A | |
| SCHEMBL30801536 | 0.81 | TRPV1 (0.70) | MAPTTRPV1HSD17B10MEN1KMT2A | |
| SCHEMBL8269764 | 0.81 | MAPT (0.79) | MAPTTRPV1HSD17B10MEN1KMT2A | |
| SCHEMBL12953572 | 0.81 | TRPV1 (0.70) | MAPTTRPV1HSD17B10MEN1KMT2A | |
| SCHEMBL20900686 | 0.79 | ERCC1 (0.57) | MAPTTRPV1HSD17B10MEN1KMT2A | |
| SCHEMBL2378518 | 0.79 | TRPV1 (0.68) | MAPTTRPV1HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115137880-B | Medical equipment with coating | 业聚医疗私人有限公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-115137880-A | Medical equipment with coating | 祥丰医疗私人有限公司 | 2022-10-04 | — | — | CN | disclosed |
| US-20210386916-A1 | MEDICAL DEVICES COATED WITH POLYDOPAMINE AND ANTIBODIES | ORBUSNEICH MEDICAL PTE. LTD. (SG) | 2021-12-16 | — | — | US | disclosed |
| US-11129926-B2 | Medical devices coated with polydopamine and antibodies | ORBUSNEICH MEDICAL PTE. LTD. (SG) | 2021-09-28 | — | — | US | disclosed |
| US-20210220523-A1 | NO RELEASING COATED PROSTHETIC VASCULAR GRAFTS | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | 2021-07-22 | — | — | US | disclosed |
| EP-3826628-A1 | NO RELEASING COATED PROSTHETIC VASCULAR GRAFTS | University of Georgia Research Foundation, Inc. (US) | 2021-06-02 | — | — | EP | disclosed |
| WO-2020041617-A1 | NO RELEASING COATED PROSTHETIC VASCULAR GRAFTS | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2020-02-27 | — | — | WO | disclosed |
| CN-110545754-A | Medical device coated with polydopamine and antibody | ORBUSNEICH MEDICAL INC | 2019-12-06 | — | — | CN | disclosed |
| EP-2950832-B1 | COATING FOR SUBSTRATE | GORE & ASS (US) | 2018-08-01 | — | — | EP | disclosed |
| US-9272075-B2 | Coating for substrate | W.L. GORE & ASSOCIATES, INC. (US) | 2016-03-01 | — | — | US | disclosed |
| EP-2950832-A1 | COATING FOR SUBSTRATE | W. L. Gore & Associates, Inc. (US) | 2015-12-09 | — | — | EP | disclosed |
| US-20140221522-A1 | COATING FOR SUBSTRATE | W. L. GORE & ASSOCIATES, INC. | 2014-08-07 | — | — | US | disclosed |
| WO-2014118382-A1 | COATING FOR SUBSTRATE | W. L. GORE & ASSOCIATES, INC. (US) | 2014-08-07 | — | — | WO | disclosed |
| WO-2014118382-A1 | COATING FOR SUBSTRATE | W. L. GORE & ASSOCIATES, INC. (US) | 2014-08-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210220523-A1 | NO RELEASING COATED PROSTHETIC VASCULAR GRAFTS | NOS2, NOS1, NOS3 | MAPT 4773/4885TRPV1 3997/4885HSD17B10 3449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.