Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 2/20 | 0.51 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA4 | P22748 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17447398 | 0.81 | PTPN11 (0.54) | LTA4HPDK2 | |
| SCHEMBL27990156 | 0.81 | PTGS2 (0.54) | LTA4HTP53RAB9APDK2SMN1; SMN2 | |
| SCHEMBL16854154 | 0.76 | AKT1 (0.46) | PDK2RPS6KA3 | |
| SCHEMBL4856586 | 0.76 | MAOB (0.54) | TAAR1LTA4HPLA2G2APDK2SMN1; SMN2 | |
| SCHEMBL4904165 | 0.76 | TAAR1 (0.75) | TAAR1LTA4HPLA2G2ATP53MAPK1 | |
| SCHEMBL19824579 | 0.76 | DRD2 (0.49) | CA12CA1CA2CA4CA9 | |
| SCHEMBL10673188 | 0.75 | SIGMAR1 (0.52) | PDK2 | |
| SCHEMBL27494752 | 0.75 | CYP2C19 (0.51) | RAB9ASMN1; SMN2 | |
| SCHEMBL13958753 | 0.75 | TAAR1 (0.67) | TAAR1LTA4HPLA2G2ATP53MAPK1 | |
| SCHEMBL9228754 | 0.75 | HDAC8 (0.43) | PDK2FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2951170-A2 | FLAP MODULATORS | Janssen Pharmaceutica, N.V. (BE) | 2015-12-09 | — | — | EP | claimed |
| WO-2014121055-A2 | FLAP MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2014-08-07 | — | — | WO | claimed |