SCHEMBL1592940

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL23872034	0.86	F2 (0.48)	XPO1F2CASP3NPC1RAB9A
	SCHEMBL17817935	0.84	CASP3 (0.42)	XPO1F2CASP3MPOMEN1
	SCHEMBL1592941	0.83	F2 (0.36)	F2CASP3CYP1A2CYP2C9CYP2C19
	SCHEMBL1592514	0.82	CHEK1 (0.38)	XPO1F2CASP3MPOPTGES
	SCHEMBL1592575	0.80	LMNA (0.51)	XPO1MEN1KMT2AMAPT
	SCHEMBL1592474	0.77	CASP3 (0.35)	XPO1F2CASP3RXFP1NPC1
	SCHEMBL1592478	0.77	CASP3 (0.39)	F2CASP3RXFP1CRHBPCRHR2
	SCHEMBL1592387	0.77	XPO1 (0.53)	XPO1MEN1KMT2AMAPT
	SCHEMBL1592549	0.77	XPO1 (0.56)	XPO1MAPT
	SCHEMBL1593077	0.77	CASP3 (0.37)	XPO1F2CASP3RXFP1PTGES

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.