SCHEMBL1592549

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29934262	1.00	XPO1 (0.56)	XPO1ALDH1A1MAPTGAAENPP3
	SCHEMBL1592361	0.88	XPO1 (0.67)	XPO1MAPTL3MBTL1SMN1; SMN2CRHR1
	SCHEMBL1592533	0.87	XPO1 (0.59)	XPO1MAPTGAAL3MBTL1SMN1; SMN2
	SCHEMBL1592551	0.84	XPO1 (0.38)	XPO1ALDH1A1MAPTGAAENPP3
	SCHEMBL1592387	0.81	XPO1 (0.53)	XPO1ALDH1A1MAPTL3MBTL1
	SCHEMBL1592940	0.77	XPO1 (0.46)	XPO1MAPT
	SCHEMBL1592575	0.73	LMNA (0.51)	XPO1ALDH1A1MAPTSMN1; SMN2LMNA
	SCHEMBL1592535	0.72	XPO1 (0.41)	XPO1MAPTGAAL3MBTL1SMN1; SMN2
	SCHEMBL1592523	0.72	XPO1 (1.00)	XPO1PARP1
	SCHEMBL23872048	0.72	XPO1 (0.52)	XPO1ALDH1A1MAPTGAAP2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.