SCHEMBL15925409

SCHEMBL15925409

Cc1ccc(-c2ccc(-c3nc(CCl)nc(C(Cl)(Cl)Cl)n3)cc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 8/20 0.36
RAB9A P51151 8/20 0.36
JAK2 O60674 1/20 0.36
HTT P42858 3/20 0.34
CYP1A2 P05177 3/20 0.34
LMNA P02545 2/20 0.34
CYP2C19 P33261 2/20 0.34
PTBP1 P26599 1/20 0.34
TNFSF10 P50591 1/20 0.34
XBP1 P17861 1/20 0.33
ATM Q13315 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
NR1H4 Q96RI1 1/20 0.33
DPP4 P27487 1/20 0.33
CYP1A1 P04798 1/20 0.32
CYP1B1 Q16678 1/20 0.32
PTGS2 P35354 1/20 0.32
ADORA3 P0DMS8 3/20 0.31
ADORA1 P30542 2/20 0.31
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4147627 0.85 NPC1 (0.40) NPC1RAB9AHTTCYP1A2LMNA
SCHEMBL17328232 0.84 MEN1 (0.37) NPC1RAB9AATMPOLBNFKB1
SCHEMBL15849066 0.84 NPC1 (0.42) NPC1RAB9ADPP4ADORA3SMN1; SMN2
SCHEMBL80269 0.83 NPC1 (0.41) NPC1RAB9AHTTCYP1A2LMNA
SCHEMBL22129836 0.83 NPC1 (0.41) NPC1RAB9AHTTCYP1A2LMNA
SCHEMBL14621998 0.83 DPP4 (0.33) NPC1RAB9AHTTATMDPP4
SCHEMBL12952424 0.82 LMNA (0.39) NPC1RAB9AJAK2HTTLMNA
SCHEMBL18344281 0.76 SDHB (0.37) NPC1RAB9AHTTCYP1A2LMNA
SCHEMBL8956226 0.74 MAPT (0.43) NPC1RAB9AHTTCYP1A2LMNA
SCHEMBL274973 0.74 GRM5 (0.41) NPC1RAB9AHTTCYP1A2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8795943-B2 Negative photoresist composition and patterning method for device LG CHEM, LTD. (KR) 2014-08-05 US disclosed