Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.34 |
| ▸ | ESR1 | P03372 | 4/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4147404 | 0.85 | MEN1 (0.46) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL15925409 | 0.84 | NPC1 (0.36) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL15849066 | 0.84 | NPC1 (0.42) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8607879 | 0.83 | MEN1 (0.48) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL14621998 | 0.83 | DPP4 (0.33) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12952424 | 0.82 | LMNA (0.39) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL8956496 | 0.74 | APP (0.40) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL13648646 | 0.74 | ALDH1A1 (0.35) | MEN1KMT2ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL8412982 | 0.73 | NPC1 (0.38) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL10710919 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150353684-A1 | HIGHLY SOLUBLE TRIS- (2, 3-EPOXYPROPYL)- ISOCYANURATE AND METHOD FOR PRODUCING SAME | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2015-12-10 | — | — | US | disclosed |