Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15933759 | 0.93 | TSHR (0.70) | TSHRTDP1 | |
| SCHEMBL15074769 | 0.93 | TSHR (0.54) | TSHRTDP1HPGDRAB9A | |
| SCHEMBL15933760 | 0.89 | TSHR (0.52) | TSHRTDP1 | |
| SCHEMBL19688992 | 0.87 | TSHR (0.48) | TSHRTDP1RAB9A | |
| SCHEMBL22605131 | 0.84 | TSHR (0.46) | TSHRTDP1 | |
| SCHEMBL19688993 | 0.82 | TSHR (0.52) | TSHRTDP1HPGDRAB9A | |
| SCHEMBL22627334 | 0.82 | TSHR (0.86) | TSHRTDP1 | |
| SCHEMBL1021081 | 0.80 | TSHR (1.00) | TSHRTDP1 | |
| SCHEMBL22627154 | 0.80 | TSHR (0.82) | TSHRTDP1 | |
| SCHEMBL19344489 | 0.79 | TSHR (0.58) | TSHRTDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014118268-A1 | 2-OXO-1,3-DIOXOLANE-4-CARBOXAMIDE BUILDING BLOCKS, THEIR PREPARATION AND USE | CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) | 2014-08-07 | — | — | WO | disclosed |
| EP-2762471-A1 | 2-oxo-1,3-dioxolane-4-carboxamide building blocks, their preparation and use | Construction Research & Technology GmbH (DE) | 2014-08-06 | — | — | EP | disclosed |