SCHEMBL15074769

SCHEMBL15074769

CC1(C)CC(NC(=O)C2COC(=O)O2)CC(C)(CNC(=O)C2COC(=O)O2)C1

nearest known ligand 0.54

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.54
TDP1 Q9NUW8 1/20 0.35
HPGD P15428 2/20 0.32
POLB P06746 1/20 0.32
RAB9A P51151 2/20 0.31
ALDH1A1 P00352 1/20 0.31
HTT P42858 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19688992 0.93 TSHR (0.48) TSHRTDP1RAB9AALDH1A1
SCHEMBL15925795 0.93 TSHR (0.66) TSHRTDP1HPGDRAB9A
SCHEMBL15933759 0.91 TSHR (0.70) TSHRTDP1
SCHEMBL22605131 0.91 TSHR (0.46) TSHRTDP1
SCHEMBL15933760 0.89 TSHR (0.52) TSHRTDP1KMT2A
SCHEMBL19688993 0.88 TSHR (0.52) TSHRTDP1HPGDPOLBRAB9A
SCHEMBL15925782 0.81 ALDH1A1 (0.44) TSHRALDH1A1
SCHEMBL15925781 0.81 ALDH1A1 (0.46) TSHRALDH1A1
SCHEMBL18721949 0.80 TSHR (0.38) TSHR
SCHEMBL19344489 0.78 TSHR (0.58) TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200339846-A1 USE OF COMPOUNDS HAVING N 2-OXO-1,3-DIOXOLANE-4-CARBOXAMIDE UNITS IN TWO-COMPONENT ADHESIVES BASF SE (DE) 2020-10-29 US disclosed
WO-2017207461-A1 USE OF COMPOUNDS HAVING N 2-OXO-1,3-DIOXOLANE-4-CARBOXAMIDE UNITS IN TWO-COMPONENT ADHESIVES BASF SE (DE) 2017-12-07 WO disclosed
US-9309218-B2 2-Oxo-1,3-dioxolane-4-carboxamides, their preparation and use CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2016-04-12 US disclosed
US-20150051365-A1 2-OXO-1,3-DIOXOLANE-4-CARBOXAMIDES, THEIR PREPARATION AND USE SIKA TECHNOLOGY AG (CH) 2015-02-19 US disclosed
WO-2013092011-A1 2-OXO-1,3-DIOXOLANE-4-CARBOXAMIDES, THEIR PREPARATION AND USE CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2013-06-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150051365-A1 2-OXO-1,3-DIOXOLANE-4-CARBOXAMIDES, THEIR PREPARATION AND USE HAO2, OXGR1, AOX1 TSHR 4470/4885TDP1 795/4885HPGD 170/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.