Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | MAN2B1 | O00754 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.30 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15925795 | 0.89 | TSHR (0.66) | TSHRTDP1 | |
| SCHEMBL15074769 | 0.89 | TSHR (0.54) | TSHRTDP1KMT2A | |
| SCHEMBL15933759 | 0.85 | TSHR (0.70) | TSHRTDP1 | |
| SCHEMBL19688992 | 0.83 | TSHR (0.48) | TSHRTDP1 | |
| SCHEMBL20865562 | 0.82 | TSHR (0.71) | TSHRGAAHCRTR2TDP1NFKB1 | |
| SCHEMBL22605131 | 0.81 | TSHR (0.46) | TSHRTDP1 | |
| SCHEMBL21065335 | 0.80 | TSHR (0.64) | TSHRGAAHCRTR2TDP1NFKB1 | |
| SCHEMBL19688993 | 0.78 | TSHR (0.52) | TSHRTDP1 | |
| SCHEMBL19344489 | 0.76 | TSHR (0.58) | TSHRTDP1 | |
| SCHEMBL18721949 | 0.75 | TSHR (0.38) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014118268-A1 | 2-OXO-1,3-DIOXOLANE-4-CARBOXAMIDE BUILDING BLOCKS, THEIR PREPARATION AND USE | CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) | 2014-08-07 | — | — | WO | disclosed |