SCHEMBL15933759

SCHEMBL15933759

COC(=O)NCC1(C)CC(NC(=O)C2COC(=O)O2)CC(C)(C)C1

nearest known ligand 0.70

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.70
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15925795 0.93 TSHR (0.66) TSHRTDP1
SCHEMBL15074769 0.91 TSHR (0.54) TSHRTDP1
SCHEMBL15933760 0.85 TSHR (0.52) TSHRTDP1
SCHEMBL19688992 0.85 TSHR (0.48) TSHRTDP1
SCHEMBL1021081 0.83 TSHR (1.00) TSHRTDP1
SCHEMBL22605131 0.82 TSHR (0.46) TSHRTDP1
SCHEMBL19344489 0.81 TSHR (0.58) TSHRTDP1
SCHEMBL19688993 0.80 TSHR (0.52) TSHRTDP1
SCHEMBL22627334 0.79 TSHR (0.86) TSHRTDP1
SCHEMBL12394889 0.78 TSHR (0.84) TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014118268-A1 2-OXO-1,3-DIOXOLANE-4-CARBOXAMIDE BUILDING BLOCKS, THEIR PREPARATION AND USE CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2014-08-07 WO disclosed