Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | NPY1R | P25929 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | CCKBR | P32239 | 1/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.38 |
| ▸ | MC3R | P41968 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2990966 | 0.94 | APP (0.45) | APPKMT2AMEN1PGRADRB2 | |
| SCHEMBL10101123 | 0.94 | APP (0.45) | APPKMT2AMEN1PGRADRB2 | |
| SCHEMBL20089651 | 0.90 | APP (0.41) | APPKMT2AMEN1PGRADRB2 | |
| SCHEMBL3361316 | 0.89 | PLA2G10 (0.36) | KMT2AMEN1IKBKBNPC1RAB9A | |
| SCHEMBL9033357 | 0.86 | GCGR (0.39) | APPKMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL9034121 | 0.86 | APP (0.41) | APPKMT2AMEN1PGRADRB2 | |
| SCHEMBL13163334 | 0.84 | APP (0.43) | APPKMT2AMEN1IKBKBNPC1 | |
| SCHEMBL13164320 | 0.83 | BACE1 (0.44) | APPKMT2AMEN1IKBKBNPC1 | |
| SCHEMBL10104552 | 0.83 | APP (0.36) | APPKMT2AMEN1PGRADRB2 | |
| SCHEMBL3858306 | 0.82 | APP (0.35) | APPKMT2AMEN1PGRADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2159227-B1 | Two-photon absorption material and application thereof | RICOH CO LTD (JP) | 2014-08-06 | — | — | EP | disclosed |