Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 5/20 | 0.36 |
| ▸ | IKBKB | O14920 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10101123 | 0.89 | APP (0.45) | APPIKBKBALDH1A1NPC1RAB9A | |
| SCHEMBL15926425 | 0.83 | APP (0.40) | APPIKBKBALDH1A1NPC1RAB9A | |
| SCHEMBL1041118 | 0.78 | ALDH1A1 (0.37) | ALDH1A1NPC1RAB9AHPGDTP53 | |
| SCHEMBL2990966 | 0.76 | APP (0.45) | APPIKBKBALDH1A1NPC1RAB9A | |
| SCHEMBL10002013 | 0.76 | APP (0.45) | APPIKBKBALDH1A1NPC1RAB9A | |
| SCHEMBL20089651 | 0.73 | APP (0.41) | APPIKBKBALDH1A1NPC1RAB9A | |
| SCHEMBL15183075 | 0.72 | APP (0.41) | APPIKBKBALDH1A1NPC1RAB9A | |
| SCHEMBL3361316 | 0.72 | PLA2G10 (0.36) | IKBKBALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL14838263 | 0.72 | TRPA1 (0.47) | APPALDH1A1NPC1RAB9AHPGD | |
| SCHEMBL21723534 | 0.72 | APP (0.46) | APPIKBKBALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8207330-B2 | Two-photon absorption material and application thereof | RICOH COMPANY, LTD. (JP) | 2012-06-26 | — | — | US | disclosed |