Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.34 |
| ▸ | F2R | P25116 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16479208 | 0.83 | SCN8A (0.46) | SMN1; SMN2CHRM2LMNACHRM1ALOX15 | |
| SCHEMBL13408057 | 0.82 | KCNK3 (0.42) | SMN1; SMN2CHRM2LMNACHRM1ALOX15 | |
| SCHEMBL1252577 | 0.79 | SMN1; SMN2 (0.45) | SMN1; SMN2HCRTR1HCRTR2SCN8AF2R | |
| SCHEMBL27051373 | 0.77 | F2R (0.44) | HIF1AF2RKDM4ERXRARXRB | |
| SCHEMBL1253226 | 0.77 | MCL1 (0.40) | KCNH2SCN8AF2RSLC6A2SLC6A4 | |
| SCHEMBL15473260 | 0.76 | RXRA (0.46) | MCHR1LMNAHIF1AL3MBTL1KDM4E | |
| SCHEMBL16952414 | 0.73 | SCN8A (0.43) | MCHR1CHRM2LMNACHRM1ALOX15 | |
| SCHEMBL15926506 | 0.72 | ALDH1A1 (0.42) | MCHR1SMN1; SMN2CHRM2LMNACHRM1 | |
| SCHEMBL16952410 | 0.72 | CHRM2 (0.38) | MCHR1SMN1; SMN2CHRM2LMNACHRM1 | |
| SCHEMBL13429929 | 0.71 | SMN1; SMN2 (0.38) | MCHR1SMN1; SMN2CHRM2LMNACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828167-B1 | ACRYLAMIDE DERIVATIVES AS ANTIBIOTIC AGENTS | DEBIOPHARM INT SA (CH) | 2014-08-06 | — | — | EP | disclosed |