Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 3/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 5/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | OXTR | P30559 | 1/20 | 0.34 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.34 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15925975 | 0.82 | P2RX7 (0.43) | P2RX7DPP4 | |
| SCHEMBL15927102 | 0.76 | USP30 (0.38) | P2RX7DPP4 | |
| SCHEMBL15927138 | 0.74 | LMNA (0.43) | LMNAKMT2AMEN1KDM4EMAPT | |
| SCHEMBL15926984 | 0.73 | USP30 (0.43) | — | |
| SCHEMBL15927101 | 0.72 | NR1H2 (0.40) | P2RX7DPP4 | |
| SCHEMBL15927048 | 0.72 | NR1H2 (0.40) | P2RX7DPP4 | |
| SCHEMBL15925961 | 0.71 | SMN1; SMN2 (0.51) | KMT2AMEN1KDM4EMAPTHTT | |
| SCHEMBL15927116 | 0.71 | P2RX7 (0.42) | P2RX7LMNAKMT2AMEN1KDM4E | |
| SCHEMBL15926967 | 0.71 | KDR (0.42) | LMNAKMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL15927160 | 0.67 | TRPA1 (0.36) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8796272-B2 | Glycine transporter-inhibiting substances | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2014-08-05 | — | — | US | disclosed |