Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | SYK | P43405 | 1/20 | 0.59 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.55 |
| ▸ | KLK5 | Q9Y337 | 3/20 | 0.53 |
| ▸ | KLK7 | P49862 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 4/20 | 0.52 |
| ▸ | CTSS | P25774 | 3/20 | 0.51 |
| ▸ | CTSL | P07711 | 2/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | ACE | P12821 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14119009 | 1.00 | ATM (0.62) | ATMSYKCTRB1KLK5KLK7 | |
| SCHEMBL8530583 | 0.93 | ATM (0.56) | ATMSYKCTRB1KLK5KLK7 | |
| SCHEMBL27878332 | 0.93 | ATM (0.56) | ATMSYKCTRB1KLK5KLK7 | |
| SCHEMBL7360205 | 0.90 | CTRB1 (0.62) | ATMSYKCTRB1APPCTSS | |
| SCHEMBL16232045 | 0.90 | ATM (0.62) | ATMSYKCTRB1KLK5APP | |
| SCHEMBL17207697 | 0.90 | SYK (0.59) | ATMSYKCTRB1KLK5KLK7 | |
| SCHEMBL6685926 | 0.90 | SYK (0.59) | ATMSYKCTRB1KLK5KLK7 | |
| SCHEMBL1262680 | 0.90 | SYK (0.59) | ATMSYKCTRB1KLK5KLK7 | |
| SCHEMBL3108565 | 0.90 | SYK (0.59) | ATMSYKCTRB1KLK5KLK7 | |
| SCHEMBL3276799 | 0.90 | SYK (0.59) | ATMSYKCTRB1KLK5KLK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8802818-B2 | Prostaglandin-F2 alpha receptor modulators and uses thereof | LUBELL WILLIAM D (CA) | 2014-08-12 | — | — | US | disclosed |