Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21498316 | 0.89 | MAPT (0.43) | PTGS2PTGS1EPHX1MAPTKMT2A | |
| SCHEMBL15929175 | 0.86 | PTGS2 (0.42) | PTGS2PTGS1FAAHEPHX1 | |
| SCHEMBL15929054 | 0.85 | PTGS2 (0.45) | PTGS2PTGS1FAAH | |
| SCHEMBL15929176 | 0.85 | PTGS2 (0.45) | PTGS2PTGS1FAAHMAPT | |
| SCHEMBL15929051 | 0.84 | PTGS2 (0.55) | PTGS2PTGS1FAAHEPHX1MAPT | |
| SCHEMBL15929177 | 0.83 | PTGS2 (0.48) | PTGS2PTGS1FAAHTRPV1 | |
| SCHEMBL15929084 | 0.82 | PTGS2 (0.42) | PTGS2PTGS1KMT2ATRPV1 | |
| SCHEMBL15929144 | 0.81 | KMT2A (0.41) | PTGS2PTGS1MAPTKMT2A | |
| SCHEMBL21498350 | 0.79 | GAA (0.42) | PTGS2MAPTHPGDKMT2A | |
| SCHEMBL21498333 | 0.78 | PTGS2 (0.34) | PTGS2PTGS1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10450260-B2 | NO- and H2S-releasing compounds | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) | 2019-10-22 | — | — | US | disclosed |
| US-20170260124-A1 | NO- AND H2S- RELEASING COMPOUNDS | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK | 2017-09-14 | — | — | US | disclosed |
| US-9688607-B2 | No- and H2S-releasing compounds | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) | 2017-06-27 | — | — | US | disclosed |
| US-20140221316-A1 | NO- AND H2S- RELEASING COMPOUNDS | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) | 2014-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221316-A1 | NO- AND H2S- RELEASING COMPOUNDS | PTGS1, NOS2, NOS1 | PTGS2 4/4885PTGS1 1/4885FAAH 645/4885 |
| US-20170260124-A1 | NO- AND H2S- RELEASING COMPOUNDS | NOS2, NOS3, NOS1 | PTGS2 9/4885PTGS1 8/4885FAAH 1545/4885 |
| US-10450260-B2 | NO- and H2S-releasing compounds | NOS2, NOS3, NOS1 | PTGS2 9/4885PTGS1 8/4885FAAH 1545/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.