Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27269115 | 0.87 | MMP12 (0.44) | KMT2AALDH1A1CYP2D6 | |
| SCHEMBL19382573 | 0.82 | CSNK1E (0.50) | TRPA1FAAHMAOBCSNK1EMAOA | |
| SCHEMBL14975377 | 0.80 | TRPA1 (0.50) | TRPA1MAOBCSNK1EKMT2AALDH1A1 | |
| SCHEMBL8063607 | 0.78 | L3MBTL1 (0.47) | MAOBL3MBTL1MAOA | |
| SCHEMBL19511954 | 0.77 | GRIK1 (0.42) | TRPA1FAAH | |
| SCHEMBL27183313 | 0.76 | TRPA1 (0.53) | TRPA1FAAH | |
| SCHEMBL560219 | 0.76 | TRPA1 (0.51) | TRPA1KMT2AALDH1A1HPGDL3MBTL1 | |
| SCHEMBL10473806 | 0.76 | TRPA1 (0.51) | TRPA1KMT2AALDH1A1HPGDL3MBTL1 | |
| SCHEMBL16058107 | 0.76 | TRPA1 (0.51) | TRPA1KMT2AALDH1A1HPGDL3MBTL1 | |
| SCHEMBL7458497 | 0.76 | RCE1 (0.45) | TRPA1FAAHMAOBCSNK1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160311804-A1 | Process | BIAL-PORTELA & CA, S.A. (PT) | 2016-10-27 | — | — | US | disclosed |
| US-9346751-B2 | Process for preparing 1, 3-Dihydroimidazole-2-Thione Derivatives | BIAL-PORTELA & CA, S.A. (PT) | 2016-05-24 | — | — | US | disclosed |
| US-20140221668-A1 | Process | BIAL-PORTELA & CA, S.A. (PT) | 2014-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221668-A1 | Process | DHPS, CYP3A5, SULT1E1 | TRPA1 2984/4885FAAH 4182/4885MAOB 1334/4885 |
| US-20160311804-A1 | Process | DHPS, CYP3A5, SULT1E1 | TRPA1 2984/4885FAAH 4182/4885MAOB 1334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.