Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.68 |
| ▸ | MAPT | P10636 | 4/20 | 0.68 |
| ▸ | POLB | P06746 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | DDX3X | O00571 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.64 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.57 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.57 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 2/20 | 0.56 |
| ▸ | CA5A | P35218 | 1/20 | 0.56 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1592637 | 0.98 | KMT2A (0.66) | KMT2AMAPTPOLBMEN1DDX3X | |
| Nitric Acid SCHEMBL2283510 | 0.97 | KMT2A (0.64) | KMT2AMAPTPOLBMEN1DDX3X | |
| SCHEMBL6725074 | 0.86 | KMT2A (0.72) | KMT2AMAPTPOLBMEN1DDX3X | |
| SCHEMBL14170 | 0.85 | KMT2A (0.75) | KMT2AMAPTPOLBMEN1DDX3X | |
| SCHEMBL10518161 | 0.84 | KMT2A (0.55) | KMT2AMAPTPOLBMEN1DDX3X | |
| SCHEMBL1880400 | 0.83 | POLB (0.68) | KMT2AMAPTPOLBMEN1DDX3X | |
| SCHEMBL29838541 | 0.83 | POLB (0.68) | KMT2AMAPTPOLBMEN1DDX3X | |
| SCHEMBL7865709 | 0.83 | SMN1; SMN2 (0.73) | KMT2AMAPTPOLBMEN1DDX3X | |
| SCHEMBL11582992 | 0.83 | POLB (0.63) | KMT2AMAPTPOLBMEN1DDX3X | |
| SCHEMBL1047211 | 0.81 | MEN1 (1.00) | KMT2AMAPTPOLBMEN1DDX3X |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4610262-A1 | MACROCYCLIC COMPOUND AS CDK9 INHIBITOR AND USE THEREOF | Artivila Biopharma (CN) | 2025-09-03 | — | — | EP | disclosed |
| WO-2024088189-A1 | MACROCYCLIC COMPOUND AS CDK9 INHIBITOR AND USE THEREOF | 科辉智药生物科技（无锡）有限公司 | 2024-05-02 | — | — | WO | disclosed |
| EP-3621952-A1 | METHOD FOR THE PRODUCTION OF PHENYLGUANIDINES OR THE SALTS THEREOF | AlzChem Trostberg GmbH (DE) | 2020-03-18 | — | — | EP | disclosed |
| WO-2018210633-A1 | METHOD FOR THE PRODUCTION OF PHENYLGUANIDINES OR THE SALTS THEREOF | ALZCHEM TROSTBERG GMBH (DE) | 2018-11-22 | — | — | WO | disclosed |
| US-9944641-B2 | Isoquinolinone derivatives useful in the treatment of cancer | PIERRE FABRE MEDICAMENT (FR) | 2018-04-17 | — | — | US | disclosed |
| US-9944641-B2 | Isoquinolinone derivatives useful in the treatment of cancer | PIERRE FABRE MEDICAMENT (FR) | 2018-04-17 | — | — | US | disclosed |
| US-9944641-B2 | Isoquinolinone derivatives useful in the treatment of cancer | PIERRE FABRE MEDICAMENT (FR) | 2018-04-17 | — | — | US | disclosed |
| US-20170240544-A1 | ISOQUINOLINONE DERIVATIVES USEFUL IN THE TREATMENT OF CANCER | PIERRE FABRE MEDICAMENT (FR) | 2017-08-24 | — | — | US | disclosed |
| US-20170240544-A1 | ISOQUINOLINONE DERIVATIVES USEFUL IN THE TREATMENT OF CANCER | PIERRE FABRE MEDICAMENT (FR) | 2017-08-24 | — | — | US | disclosed |
| US-20170240544-A1 | ISOQUINOLINONE DERIVATIVES USEFUL IN THE TREATMENT OF CANCER | PIERRE FABRE MEDICAMENT (FR) | 2017-08-24 | — | — | US | disclosed |
| WO-2003051886-A1 | PYRAZOLOPYRIDAZINE DERIVATIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2003-06-26 | — | — | WO | disclosed |
| US-20030096816-A1 | Inhibitors of c-Jun N-terminal kinases (JNK) and other protein kinases | VERTEX PHARMACEUTICALS INCORPORATED | 2003-05-22 | — | — | US | disclosed |
| US-20030036529-A1 | Compositions and methods for inhibiting arginase activity | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2003-02-20 | — | — | US | disclosed |
| WO-2003004492-A1 | ISOXAZOLYL-PYRIMIDINES AS INHIBITORS OF SRC AND LCK PROTEIN KINASES | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2003-01-16 | — | — | WO | disclosed |
| WO-2002083667-A2 | INHIBITORS OF C-JUN N-TERMINAL KINASES (JNK) AND OTHER PROTEIN KINASES | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2002-10-24 | — | — | WO | disclosed |
| US-6387890-B1 | CARDIOVASCULAR DISORDERS; GASTROINTESTINAL DISORDERS; SEXUAL DISORDERS | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2002-05-14 | — | — | US | disclosed |
| EP-1049660-A1 | COMPOSITIONS AND METHODS FOR INHIBITING ARGINASE ACTIVITY | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2000-11-08 | — | — | EP | disclosed |
| CN-1043531-C | Pyrimidine derivatives and a process for production thereof | NOVATIS AG (CH) | 1999-06-02 | — | — | CN | disclosed |
| WO-1999019295-A1 | COMPOSITIONS AND METHODS FOR INHIBITING ARGINASE ACTIVITY | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 1999-04-22 | — | — | WO | disclosed |
| CN-1077713-A | Pyrimidine derivatives and preparation method thereof | CIBA GEIGY AG (CH) | 1993-10-27 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030096816-A1 | Inhibitors of c-Jun N-terminal kinases (JNK) and other protein kinases | LCK, MAPK1, MAP3K1 | KMT2A 3261/4885MAPT 2790/4885POLB 3108/4885 |
| US-20170240544-A1 | ISOQUINOLINONE DERIVATIVES USEFUL IN THE TREATMENT OF CANCER | TP53, KRAS, AQP1 | KMT2A 1365/4885MAPT 2029/4885POLB 925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.