Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.75 |
| ▸ | MEN1 | O00255 | 5/20 | 0.75 |
| ▸ | MAPT | P10636 | 5/20 | 0.75 |
| ▸ | POLB | P06746 | 3/20 | 0.75 |
| ▸ | HTT | P42858 | 2/20 | 0.75 |
| ▸ | DDX3X | O00571 | 1/20 | 0.75 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.71 |
| ▸ | BLM | P54132 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | CA12 | O43570 | 2/20 | 0.61 |
| ▸ | CA1 | P00915 | 2/20 | 0.61 |
| ▸ | CA2 | P00918 | 2/20 | 0.61 |
| ▸ | CA9 | Q16790 | 2/20 | 0.61 |
| ▸ | CA5A | P35218 | 1/20 | 0.61 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1047211 | 0.86 | MEN1 (1.00) | KMT2AMEN1MAPTPOLBHTT | |
| SCHEMBL1592991 | 0.85 | KMT2A (0.68) | KMT2AMEN1MAPTPOLBHTT | |
| SCHEMBL1880400 | 0.85 | POLB (0.68) | KMT2AMEN1MAPTPOLBHTT | |
| SCHEMBL29838541 | 0.85 | POLB (0.68) | KMT2AMEN1MAPTPOLBHTT | |
| SCHEMBL11582992 | 0.85 | POLB (0.63) | KMT2AMEN1MAPTPOLBHTT | |
| SCHEMBL1694713 | 0.84 | KMT2A (0.77) | KMT2AMEN1MAPTPOLBHTT | |
| SCHEMBL17084065 | 0.84 | MEN1 (0.96) | KMT2AMEN1MAPTPOLBHTT | |
| SCHEMBL1694714 | 0.84 | KMT2A (0.77) | KMT2AMEN1MAPTPOLBHTT | |
| SCHEMBL18530327 | 0.84 | ALDH1A1 (0.68) | KMT2AMEN1MAPTPOLBHTT | |
| Hydrochloric Acid SCHEMBL1592637 | 0.83 | KMT2A (0.66) | KMT2AMEN1MAPTPOLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023021496-A2 | NOVEL UREA ANALOGUES CONTAINING 5-AMINO URACIL: ONE-POT GREEN SYNTHESIS AND IN VITRO BIOLOGICAL EVALUATION | KING KHALID UNIVERSITY (SA) | 2023-02-23 | — | — | WO | claimed |
| EP-3555189-B1 | REPAIRABLE POLYMER COMPOSITIONS | KINECTRICS UK LTD (GB) | 2022-03-16 | — | — | EP | claimed |
| EP-3555189-A1 | REPAIRABLE POLYMER COMPOSITIONS | Gnosys Global Limited (GB) | 2019-10-23 | — | — | EP | claimed |
| WO-2018109487-A1 | REPAIRABLE POLYMER COMPOSITIONS | THE UNIVERSITY OF READING (GB) | 2018-06-21 | — | — | WO | claimed |
| WO-2002039987-A2 | USE OF MALARIA PARASITE ANION CHANNEL BLOCKERS FOR TREATING MALARIA | NEUROSEARCH A/S (DK) | 2002-05-23 | — | — | WO | claimed |
| EP-1005459-A1 | SUBSTITUTED ISOQUINOLINES AS ANTICONVULSIVANTS | SMITHKLINE BEECHAM PLC (GB) | 2000-06-07 | — | — | EP | claimed |
| WO-1999014197-A1 | SUBSTITUTED ISOQUINOLINES AS ANTICONVULSIVANTS | SMITHKLINE BEECHAM PLC (GB) | 1999-03-25 | — | — | WO | claimed |
| CN-1075717-A | Benzodiazepine * derivatives | YAMANOUCHI PHARMA CO LTD (JP) | 1993-09-01 | — | — | CN | claimed |
| CN-115974768-B | Preparation method and application of piperlonguminine derivatives containing diaryl urea structure | 贵州大学 | 2024-09-27 | — | — | CN | disclosed |
| CN-117736059-A | Green preparation method of N, N-disubstituted urea and derivative | 宁夏大学 | 2024-03-22 | — | — | CN | disclosed |
| US-11814385-B2 | Small molecule inhibitors targeting Clostridioides difficile sporulation | UNIVERSITY OF SOUTH FLORIDA (US) | 2023-11-14 | — | — | US | disclosed |
| US-11814385-B2 | Small molecule inhibitors targeting Clostridioides difficile sporulation | UNIVERSITY OF SOUTH FLORIDA (US) | 2023-11-14 | — | — | US | disclosed |
| CN-115974768-A | Preparation method and application of piperlonguminine derivatives containing diaryl urea structure | 贵州大学 | 2023-04-18 | — | — | CN | disclosed |
| US-20230002381-A1 | SMALL MOLECULE INHIBITORS TARGETING CLOSTRIDIOIDES DIFFICILE SPORULATION | NATIONAL INSTITUTES OF HEALTH | 2023-01-05 | — | — | US | disclosed |
| WO-2003024439-A1 | PHENETHANOLAMINE DERIVATIVES FOR TREATMENT OF RESPIRATORY DISEASES | GLAXO GROUP LIMITED (GB) | 2003-03-27 | — | — | WO | disclosed |
| CN-1071746-C | Amidine derivatives with nitric oxide synthetase activities | ASTERA CO (SE) | 2001-09-26 | — | — | CN | disclosed |
| CN-1132505-A | Amidine derivatives with nitric oxide synthetase activities | ASTERA CO (SE) | 1996-10-02 | — | — | CN | disclosed |
| US-5380941-A | From the phenylurea and an amine with the sulfur group | BASF AKTIENGESELLSCHAFT (DE) | 1995-01-10 | — | — | US | disclosed |
| CN-1075717-A | Benzodiazepine * derivatives | YAMANOUCHI PHARMA CO LTD (JP) | 1993-09-01 | — | — | CN | disclosed |
| CN-1074678-A | 1, the 5-benzodiazepine derivatives | GLAXO SPA (IT) | 1993-07-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230002381-A1 | SMALL MOLECULE INHIBITORS TARGETING CLOSTRIDIOIDES DIFFICILE SPORULATION | SPOUT1, CLPP, RPN2 | KMT2A 4130/4885MEN1 4676/4885MAPT 3389/4885 |
| US-11814385-B2 | Small molecule inhibitors targeting Clostridioides difficile sporulation | SPOUT1, CLPP, RPN2 | KMT2A 4130/4885MEN1 4676/4885MAPT 3389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.