SCHEMBL15932302

SCHEMBL15932302

CCOC(=O)c1cc(COc2cccc(F)c2)on1

nearest known ligand 0.53

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 8/20 0.53
KMT2A Q03164 4/20 0.53
NPC1 O15118 4/20 0.53
MEN1 O00255 2/20 0.53
MAPT P10636 2/20 0.49
KDM4E B2RXH2 1/20 0.47
MRGPRX4 Q96LA9 1/20 0.46
LMNA P02545 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17298745 0.88 RAB9A (0.54) RAB9AKMT2ANPC1MEN1MAPT
SCHEMBL17288680 0.86 ALDH1A1 (0.52) RAB9AKMT2ANPC1MEN1MAPT
SCHEMBL15932182 0.86 MAPT (0.63) RAB9AKMT2ANPC1MEN1MAPT
SCHEMBL15931961 0.86 RAB9A (0.56) RAB9AKMT2ANPC1MEN1MAPT
SCHEMBL15931957 0.86 RAB9A (0.53) RAB9AKMT2ANPC1MEN1MAPT
SCHEMBL15931947 0.86 L3MBTL1 (0.53) RAB9AKMT2ANPC1MEN1MAPT
SCHEMBL15931841 0.85 RAB9A (0.72) RAB9AKMT2ANPC1MEN1
SCHEMBL15932121 0.84 NR4A2 (0.51) RAB9AKMT2ANPC1MEN1MRGPRX4
SCHEMBL15931706 0.82 RAB9A (0.53) RAB9AKMT2ANPC1MEN1MAPT
SCHEMBL15932185 0.82 SLC26A6 (0.47) RAB9AKMT2ANPC1MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2952096-B1 Amide compound, an arthropod pest control agent and a method for controlling arthropod pest SUMITOMO CHEMICAL CO (JP) 2018-04-04 EP disclosed
US-9814235-B2 Method for controlling arthropod pest SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-11-14 US disclosed
US-9814235-B2 Method for controlling arthropod pest SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-11-14 US disclosed
US-9814235-B2 Method for controlling arthropod pest SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-11-14 US disclosed
EP-2952096-A1 METHOD FOR CONTROLLING ARTHROPOD PEST Sumitomo Chemical Company, Limited (JP) 2015-12-09 EP disclosed
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-03 US disclosed
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-03 US disclosed
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-03 US disclosed
WO-2014119696-A1 METHOD FOR CONTROLLING ARTHROPOD PEST 住友化学株式会社 (JP) 2014-08-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST H1-0, H1-3, H1-2 RAB9A 400/4885KMT2A 393/4885NPC1 3630/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.