Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 6/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | BAX | Q07812 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.38 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23654380 | 0.81 | PARP15 (0.42) | PARP10 | |
| SCHEMBL19622327 | 0.78 | CA12 (0.44) | SMN1; SMN2CA1CA2 | |
| SCHEMBL19622230 | 0.78 | HDAC3 (0.36) | TSHRSMN1; SMN2PARP10 | |
| SCHEMBL2093112 | 0.77 | LTA4H (0.55) | LTA4HNR1H2BAXTSHRGSTP1 | |
| SCHEMBL17787354 | 0.77 | KDM4E (0.44) | BAZ2BBAZ2A | |
| SCHEMBL11391950 | 0.76 | LTA4H (0.53) | LTA4HNR1H2BAXTSHRGSTP1 | |
| SCHEMBL6184207 | 0.76 | LTA4H (0.53) | LTA4HNR1H2BAXTSHRGSTP1 | |
| SCHEMBL20439168 | 0.76 | LTA4H (0.53) | LTA4HNR1H2BAXTSHRGSTP1 | |
| SCHEMBL10269524 | 0.76 | LTA4H (0.44) | LTA4HNR1H2BAXTSHRSMN1; SMN2 | |
| SCHEMBL11255857 | 0.76 | LTA4H (0.53) | LTA4HNR1H2BAXTSHRGSTP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140221631-A1 | BORON-CONTAINING SMALL MOLECULES | ANACOR PHARMACEUTICALS, INC. (US) | 2014-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221631-A1 | BORON-CONTAINING SMALL MOLECULES | ETF1, POLR1C, DPM1 | LTA4H 3905/4885NR1H2 4332/4885BAX 787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.