Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.40 |
| ▸ | CKS1B | P61024 | 2/20 | 0.39 |
| ▸ | SKP1 | P63208 | 2/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15933682 | 0.88 | GBA1 (0.52) | GPR119P2RX7CKS1BSKP1SKP2 | |
| SCHEMBL4399124 | 0.86 | GPR119 (0.46) | GPR119HTTATMP2RX7NR1H2 | |
| SCHEMBL17298980 | 0.83 | F2RL1 (0.45) | P2RX7 | |
| SCHEMBL15933695 | 0.80 | EGLN2 (0.48) | GPR119HTTATMP2RX7 | |
| SCHEMBL15933586 | 0.80 | GPR119 (0.52) | GPR119NR1H2 | |
| SCHEMBL2813207 | 0.78 | SMARCA2 (0.53) | GPR119HTTATMP2RX7CKS1B | |
| SCHEMBL15933470 | 0.78 | NR1H2 (0.41) | HTTATMCKS1BSKP1SKP2 | |
| SCHEMBL23390025 | 0.77 | GRM5 (0.44) | GPR119HTTATMP2RX7CKS1B | |
| SCHEMBL29796413 | 0.77 | GRM5 (0.44) | GPR119HTTATMP2RX7CKS1B | |
| SCHEMBL15933636 | 0.77 | P2RX7 (0.43) | GPR119P2RX7CKS1BSKP1SKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014117318-A1 | NOVEL TRIAZOLE ANTIFUNGAL COMPOUNDS, AND PHARMACEUTICAL COMPOSITION, PREPARATION METHOD, AND APPLICATION THEREOF | 中国科学院上海药物研究所 (CN) | 2014-08-07 | — | — | WO | disclosed |