Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.52 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.48 |
| ▸ | KIT | P10721 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.44 |
| ▸ | CKS1B | P61024 | 2/20 | 0.43 |
| ▸ | SKP1 | P63208 | 2/20 | 0.43 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | WDR5 | P61964 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15933469 | 0.88 | GPR119 (0.43) | GBA1GPR119KITP2RX7CKS1B | |
| SCHEMBL4399124 | 0.88 | GPR119 (0.46) | GPR119P2RX7GRM1POLBMAPK1 | |
| SCHEMBL17298980 | 0.82 | F2RL1 (0.45) | P2RX7GRM5GRM1KDM1ANAMPT | |
| SCHEMBL15933636 | 0.81 | P2RX7 (0.43) | GPR119P2RX7CKS1BSKP1SKP2 | |
| SCHEMBL2813207 | 0.80 | SMARCA2 (0.53) | GPR119P2RX7CKS1BSKP1SKP2 | |
| SCHEMBL15933695 | 0.80 | EGLN2 (0.48) | GPR119P2RX7 | |
| SCHEMBL15933586 | 0.79 | GPR119 (0.52) | GPR119NR1H2 | |
| SCHEMBL23390025 | 0.79 | GRM5 (0.44) | GPR119P2RX7GRM5CKS1BSKP1 | |
| SCHEMBL29796413 | 0.79 | GRM5 (0.44) | GPR119P2RX7GRM5CKS1BSKP1 | |
| SCHEMBL4399119 | 0.76 | NR1H2 (0.55) | GBA1GPR119KITGRM5GRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014117318-A1 | NOVEL TRIAZOLE ANTIFUNGAL COMPOUNDS, AND PHARMACEUTICAL COMPOSITION, PREPARATION METHOD, AND APPLICATION THEREOF | 中国科学院上海药物研究所 (CN) | 2014-08-07 | — | — | WO | disclosed |