Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.52 |
| ▸ | RET | P07949 | 12/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15933695 | 0.87 | EGLN2 (0.48) | GPR119RETJAK2JAK1EGLN2 | |
| SCHEMBL25431198 | 0.83 | GPR119 (0.45) | GPR119EGLN2NR1H2 | |
| SCHEMBL15933677 | 0.81 | GPR119 (0.53) | GPR119RETJAK2JAK1EGLN2 | |
| SCHEMBL15933636 | 0.81 | P2RX7 (0.43) | GPR119RETEGLN2 | |
| SCHEMBL17298980 | 0.81 | F2RL1 (0.45) | — | |
| SCHEMBL16836256 | 0.81 | RET (0.42) | GPR119RET | |
| SCHEMBL31098398 | 0.81 | RET (0.42) | GPR119RET | |
| SCHEMBL4399124 | 0.80 | GPR119 (0.46) | GPR119NR1H2 | |
| SCHEMBL15933469 | 0.80 | GPR119 (0.43) | GPR119NR1H2 | |
| SCHEMBL15933682 | 0.79 | GBA1 (0.52) | GPR119NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014117318-A1 | NOVEL TRIAZOLE ANTIFUNGAL COMPOUNDS, AND PHARMACEUTICAL COMPOSITION, PREPARATION METHOD, AND APPLICATION THEREOF | 中国科学院上海药物研究所 (CN) | 2014-08-07 | — | — | WO | disclosed |