SCHEMBL1593349

SCHEMBL1593349

O=P([O-])([O-])Oc1ccccc1S(=O)(=O)O.O=P([O-])([O-])Oc1ccccc1S(=O)(=O)O.[Zr+4]

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 4/20 0.37
MYC P01106 1/20 0.35
ELANE P08246 1/20 0.34
TTR P02766 2/20 0.33
TSHR P16473 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
PGAM1 P18669 1/20 0.33
HTR6 P50406 1/20 0.33
SRC P12931 1/20 0.33
KDM4E B2RXH2 1/20 0.33
USP2 O75604 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
PDE3A Q14432 1/20 0.33
HSD17B10 Q99714 1/20 0.33
INPPL1 O15357 1/20 0.32
INPP5B P32019 1/20 0.32
INPP5A Q14642 1/20 0.32
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2196909 0.83 MYC (0.38) MYCELANETTRTSHRSMN1; SMN2
SCHEMBL2175835 0.81 INPPL1 (0.52) MYCELANESRCKDM4EUSP2
SCHEMBL1593348 0.80 INPPL1 (0.50) MYCELANESRCKDM4EUSP2
SCHEMBL28618568 0.76 SRC (0.44) TSHRSRCKDM4EALDH1A1CA12
SCHEMBL22442051 0.75 MYC (0.40) MYCELANETTRTSHRSMN1; SMN2
SCHEMBL8983185 0.74 MYC (0.42) MYCELANETTRTSHRSMN1; SMN2
SCHEMBL5698446 0.74 MYC (0.42) MYCELANETTRTSHRSMN1; SMN2
SCHEMBL4962913 0.72 MYC (0.41) MYCELANETTRTSHRSMN1; SMN2
SCHEMBL28521154 0.72 MYC (0.41) MYCELANETTRTSHRSMN1; SMN2
SCHEMBL6160456 0.72 SMN1; SMN2 (0.46) MYCELANETTRTSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9023553-B2 Multilayered composite proton exchange membrane and a process for manufacturing the same CHEMSULTANTS INTERNATIONAL, INC. (US) 2015-05-05 US claimed
US-20150299877-A1 MATERIAL FOR AN ELECTROCHEMICAL DEVICE CERAM HYD (FR) 2015-10-22 US disclosed
US-9105907-B2 Material for an electrochemical device CERAM HYD (FR) 2015-08-11 US disclosed
US-9023553-B2 Multilayered composite proton exchange membrane and a process for manufacturing the same CHEMSULTANTS INTERNATIONAL, INC. (US) 2015-05-05 US disclosed
US-20140107135-A1 PYRIMIDINONE INHIBITORS OF LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 AUSPEX PHARMACEUTICALS, INC. (US) 2014-04-17 US disclosed
US-8507147-B2 Proton exchange membrane and cell comprising such a membrane CERAM HYD (FR) 2013-08-13 US disclosed
US-8383692-B2 Method of activating boron nitride CERAM HYD (FR) 2013-02-26 US disclosed
US-7977008-B2 High temperature proton exchange membrane using ionomer/solid proton conductor, preparation method thereof and fuel cell containing the same Industry-University Cooperation Foundation Sogang University (KR) 2011-07-12 US disclosed
US-7973109-B2 Crosslinked type layered metal phosphonate compound, production process therefor, non-crosslinked type layered metal phosphonate compound, production process therefor, as well as stock solution KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) 2011-07-05 US disclosed
US-20110091789-A1 MATERIAL FOR AN ELECTROCHEMICAL DEVICE CERAM HYD (FR) 2011-04-21 US disclosed
US-20100279201-A1 PROTON EXCHANGE MEMBRANE AND CELL COMPRISING SUCH A MEMBRANE CERAM HYD (FR) 2010-11-04 US disclosed
US-20100280138-A1 METHOD OF ACTIVATING BORON NITRIDE GEN-HY (FR) 2010-11-04 US disclosed
US-20090176141-A1 Multilayered composite proton exchange membrane and a process for manufacturing the same CHEMSULTANTS INTERNATIONAL, INC. (US) 2009-07-09 US disclosed
WO-2009073055-A1 MULTILAYERED COMPOSITE PROTON EXCHANGE MEMBRANE AND A PROCESS FOR MANUFACTURING THE SAME CHEMSULTANTS INTERNATIONAL, INC. (US) 2009-06-11 WO disclosed
US-20090093607-A1 Crosslinked type layered metal phosphonate compound, production process therefor, non-crosslinked type layered metal phosphonate compound, production process therefor, as well as stock solution KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) 2009-04-09 US disclosed
US-20070026284-A1 High temperature proton exchange membrane using ionomer/soild proton conductor, preparation method thereof and fuel cell containing the same INDUSTRY-UNIVERSITY COOPERATION FOUNDATION (KR) 2007-02-01 US disclosed
WO-2005006474-A1 HIGH TEMPERATURE PROTON EXCHANGE MEMBRANE USING IONOMER/SOILD PROTON CONDUCTOR, PREPARATION METHOD THEREOF AND FUEL CELL CONTAINING THE SAME SOGANG UNIVERSITY (KR) 2005-01-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090093607-A1 Crosslinked type layered metal phosphonate compound, production process therefor, non-crosslinked type layered metal phosphonate compound, production process therefor, as well as stock solution WEE1, WEE2, PPIP5K2 GPR84 4772/4885MYC 4385/4885ELANE 4868/4885
US-20140107135-A1 PYRIMIDINONE INHIBITORS OF LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 PLA2G1B, PLA2G4A, PLA2G4B GPR84 1013/4885MYC 4811/4885ELANE 403/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.