SCHEMBL1593348

SCHEMBL1593348

O=P(O)(O)Oc1ccccc1S(=O)(=O)O.[Zr]

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
INPPL1 O15357 11/20 0.50
INPP5A Q14642 6/20 0.50
INPP5B P32019 2/20 0.50
SRC P12931 5/20 0.49
KDM4E B2RXH2 1/20 0.49
USP2 O75604 1/20 0.49
ALDH1A1 P00352 1/20 0.49
HPGD P15428 1/20 0.49
PDE3A Q14432 1/20 0.49
HSD17B10 Q99714 1/20 0.49
AKT1 P31749 1/20 0.44
MYC P01106 1/20 0.36
ELANE P08246 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2175835 0.98 INPPL1 (0.52) INPPL1INPP5AINPP5BSRCKDM4E
SCHEMBL2196909 0.85 MYC (0.38) INPPL1INPP5AINPP5BSRCKDM4E
SCHEMBL9315209 0.81 INPPL1 (0.50) INPPL1INPP5AINPP5BSRCKDM4E
SCHEMBL28712123 0.81 ELANE (0.56) INPPL1INPP5AINPP5BSRCKDM4E
SCHEMBL1593349 0.80 GPR84 (0.37) INPPL1INPP5AINPP5BSRCKDM4E
SCHEMBL28618568 0.77 SRC (0.44) SRCKDM4EALDH1A1
SCHEMBL2573126 0.77 INPPL1 (0.70) INPPL1INPP5AINPP5BSRCKDM4E
SCHEMBL28494979 0.77 INPPL1 (0.39) INPPL1INPP5AINPP5BSRCKDM4E
SCHEMBL5698446 0.76 MYC (0.42) ALDH1A1HSD17B10MYCELANE
SCHEMBL8983185 0.76 MYC (0.42) ALDH1A1HSD17B10MYCELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9023553-B2 Multilayered composite proton exchange membrane and a process for manufacturing the same CHEMSULTANTS INTERNATIONAL, INC. (US) 2015-05-05 US claimed
US-20150299877-A1 MATERIAL FOR AN ELECTROCHEMICAL DEVICE CERAM HYD (FR) 2015-10-22 US disclosed
US-9105907-B2 Material for an electrochemical device CERAM HYD (FR) 2015-08-11 US disclosed
US-9023553-B2 Multilayered composite proton exchange membrane and a process for manufacturing the same CHEMSULTANTS INTERNATIONAL, INC. (US) 2015-05-05 US disclosed
US-20140107135-A1 PYRIMIDINONE INHIBITORS OF LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 AUSPEX PHARMACEUTICALS, INC. (US) 2014-04-17 US disclosed
US-8507147-B2 Proton exchange membrane and cell comprising such a membrane CERAM HYD (FR) 2013-08-13 US disclosed
US-8383692-B2 Method of activating boron nitride CERAM HYD (FR) 2013-02-26 US disclosed
US-7977008-B2 High temperature proton exchange membrane using ionomer/solid proton conductor, preparation method thereof and fuel cell containing the same Industry-University Cooperation Foundation Sogang University (KR) 2011-07-12 US disclosed
US-7973109-B2 Crosslinked type layered metal phosphonate compound, production process therefor, non-crosslinked type layered metal phosphonate compound, production process therefor, as well as stock solution KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) 2011-07-05 US disclosed
US-20110091789-A1 MATERIAL FOR AN ELECTROCHEMICAL DEVICE CERAM HYD (FR) 2011-04-21 US disclosed
US-20100279201-A1 PROTON EXCHANGE MEMBRANE AND CELL COMPRISING SUCH A MEMBRANE CERAM HYD (FR) 2010-11-04 US disclosed
US-20100280138-A1 METHOD OF ACTIVATING BORON NITRIDE GEN-HY (FR) 2010-11-04 US disclosed
US-20090176141-A1 Multilayered composite proton exchange membrane and a process for manufacturing the same CHEMSULTANTS INTERNATIONAL, INC. (US) 2009-07-09 US disclosed
WO-2009073055-A1 MULTILAYERED COMPOSITE PROTON EXCHANGE MEMBRANE AND A PROCESS FOR MANUFACTURING THE SAME CHEMSULTANTS INTERNATIONAL, INC. (US) 2009-06-11 WO disclosed
US-20090093607-A1 Crosslinked type layered metal phosphonate compound, production process therefor, non-crosslinked type layered metal phosphonate compound, production process therefor, as well as stock solution KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) 2009-04-09 US disclosed
US-20070026284-A1 High temperature proton exchange membrane using ionomer/soild proton conductor, preparation method thereof and fuel cell containing the same INDUSTRY-UNIVERSITY COOPERATION FOUNDATION (KR) 2007-02-01 US disclosed
WO-2005006474-A1 HIGH TEMPERATURE PROTON EXCHANGE MEMBRANE USING IONOMER/SOILD PROTON CONDUCTOR, PREPARATION METHOD THEREOF AND FUEL CELL CONTAINING THE SAME SOGANG UNIVERSITY (KR) 2005-01-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090093607-A1 Crosslinked type layered metal phosphonate compound, production process therefor, non-crosslinked type layered metal phosphonate compound, production process therefor, as well as stock solution WEE1, WEE2, PPIP5K2 INPPL1 64/4885INPP5A 68/4885INPP5B 26/4885
US-20140107135-A1 PYRIMIDINONE INHIBITORS OF LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 PLA2G1B, PLA2G4A, PLA2G4B INPPL1 240/4885INPP5A 223/4885INPP5B 113/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.