Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16520582 | 0.82 | CYP1A2 (0.38) | EPHX1ALDH1A1TSHR | |
| SCHEMBL9895608 | 0.79 | EPHX1 (0.31) | EPHX1TSHR | |
| SCHEMBL13242767 | 0.78 | — | — | |
| SCHEMBL13679324 | 0.77 | EPHX1 (0.36) | EPHX1 | |
| SCHEMBL1352530 | 0.77 | — | — | |
| SCHEMBL18626278 | 0.77 | EPHX1 (0.32) | EPHX1 | |
| SCHEMBL11420167 | 0.77 | ALDH1A1 (0.40) | EPHX1ALDH1A1TSHRPOLBHSD17B10 | |
| SCHEMBL12027549 | 0.77 | GAA (0.39) | ALDH1A1TSHRPOLBHSD17B10 | |
| SCHEMBL782180 | 0.75 | EPHX1 (0.31) | EPHX1TSHR | |
| SCHEMBL15931191 | 0.74 | EPHX1 (0.30) | EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9518053-B2 | Fluorinated integrin antagonists | SCIFLUOR LIFE SCIENCES, INC. (US) | 2016-12-13 | — | — | US | disclosed |
| US-20160130270-A1 | FLUORINATED 3-(2-OXO-3-(3-ARYLPROPYL)IMIDAZOLIDIN-1-YL)-3-ARYLPROPANOIC ACID DERIVATIVES | FELIQS CORPORATION (JP) | 2016-05-12 | — | — | US | disclosed |
| US-9266884-B2 | Fluorinated 3-(2-oxo-3-(3-arylpropyl)imidazolidin-1-y1)-3-arylpropanoic acid derivatives | SCIFLUOR LIFE SCIENCES, INC. (US) | 2016-02-23 | — | — | US | disclosed |
| US-20150057308-A1 | Fluorinated 3-(2-Oxo-3-(3-Arylpropyl)Imidazolidin-1-yl)-3-Arylpropanoic Acid Derivatives | FELIQS CORPORATION (JP) | 2015-02-26 | — | — | US | disclosed |
| US-8901144-B2 | Fluorinated 3-(2-oxo-3-(3-arylpropyl)imidazolidin-1-yl)-3-arylpropanoic acid derivatives | SCIFLUOR LIFE SCIENCES, LLC (US) | 2014-12-02 | — | — | US | disclosed |
| US-20140221410-A1 | Fluorinated 3-(2-Oxo-3-(3-Arylpropyl)Imidazolidin-1-yl)-3-Arylpropanoic Acid Derivatives | SCIFLUOR LIFE SCIENCES, LLC (US) | 2014-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150057308-A1 | Fluorinated 3-(2-Oxo-3-(3-Arylpropyl)Imidazolidin-1-yl)-3-Arylpropanoic Acid Derivatives | ITGB3, ITGA2, ITGA1 | EPHX1 1967/4885ALDH1A1 765/4885TDP1 4358/4885 |
| US-20160130270-A1 | FLUORINATED 3-(2-OXO-3-(3-ARYLPROPYL)IMIDAZOLIDIN-1-YL)-3-ARYLPROPANOIC ACID DERIVATIVES | ITGB3, ITGA2, ITGA1 | EPHX1 1967/4885ALDH1A1 765/4885TDP1 4358/4885 |
| US-20140221410-A1 | Fluorinated 3-(2-Oxo-3-(3-Arylpropyl)Imidazolidin-1-yl)-3-Arylpropanoic Acid Derivatives | ITGB3, ITGA2, ITGA1 | EPHX1 1967/4885ALDH1A1 765/4885TDP1 4358/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.