Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.46 |
| ▸ | CCR3 | P51677 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14048171 | 0.87 | ACHE (0.49) | ACHEKDM4EALDH1A1GLAGAA | |
| SCHEMBL15933738 | 0.84 | CXCR4 (0.56) | ACHEKDM4EALDH1A1MAPT | |
| SCHEMBL15933901 | 0.84 | MBTD1 (0.60) | ACHEKDM4EALDH1A1GLAGAA | |
| SCHEMBL15933900 | 0.84 | MAPT (0.68) | ACHEKDM4EALDH1A1GLAGAA | |
| SCHEMBL14048044 | 0.84 | F10 (0.49) | ACHEKDM4EALDH1A1GLAGAA | |
| SCHEMBL544141 | 0.83 | CCR3 (0.67) | ACHEALDH1A1PRMT6CCR3 | |
| Hydrochloric Acid SCHEMBL6092095 | 0.81 | CCR3 (0.65) | ACHEALDH1A1PRMT6CCR3 | |
| SCHEMBL14220887 | 0.81 | CHRM2 (0.51) | ACHEKDM4EALDH1A1GLAGAA | |
| SCHEMBL8825661 | 0.81 | SIGMAR1 (0.62) | ACHEKDM4EALDH1A1MAPT | |
| SCHEMBL15933762 | 0.81 | CCR3 (0.45) | KDM4EALDH1A1GLAGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014117669-A1 | BENZISOSELENAZOLONE-CONTAINING DONEPEZIL ANALOG | 中山大学 (CN) | 2014-08-07 | — | — | WO | disclosed |