SCHEMBL15935113

SCHEMBL15935113

Cc1cc(N=Nc2cc(C)c(N=Nc3ccc4cc(N=Nc5ccc(O)cc5)ccc4c3O)cc2C)ccc1N=Nc1ccc(N=Nc2cc3c(S(=O)(=O)O)cccc3cc2S(=O)(=O)O)c(C)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATIC P31939 3/20 0.48
CTRB1 P17538 1/20 0.46
SUMO2 P61956 2/20 0.45
SUMO1 P63165 2/20 0.45
SENP7 Q9BQF6 2/20 0.45
SENP2 Q9HC62 2/20 0.45
ENPP2 Q13822 6/20 0.44
CYP1A2 P05177 2/20 0.44
BRD4 O60885 1/20 0.42
MPL P40238 1/20 0.42
CTRC Q99895 1/20 0.42
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
ALDH1A1 P00352 2/20 0.41
HIF1A Q16665 1/20 0.41
KDM4E B2RXH2 1/20 0.40
TP53 P04637 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15935111 0.94 ATIC (0.48) ATICCTRB1SUMO2SUMO1SENP7
SCHEMBL15935143 0.93 BRD4 (0.51) ATICCTRB1SUMO2SUMO1SENP7
SCHEMBL17460863 0.93 ATIC (0.52) ATICCTRB1SUMO2SUMO1SENP7
SCHEMBL15935147 0.92 ATIC (0.51) ATICCTRB1SUMO2SUMO1SENP7
SCHEMBL15935141 0.91 MEN1 (0.48) ATICCTRB1SUMO2SUMO1SENP7
SCHEMBL15935145 0.89 ATIC (0.50) ATICCTRB1SUMO2SUMO1SENP7
SCHEMBL17460875 0.87 ATIC (0.46) ATICCTRB1SUMO2SUMO1SENP7
SCHEMBL17460874 0.87 PHLPP2 (0.50) ATICCTRB1SUMO2SUMO1SENP7
SCHEMBL15935140 0.87 ENPP2 (0.54) ATICCTRB1SUMO2SUMO1SENP7
SCHEMBL15935144 0.87 ENPP2 (0.49) ATICCTRB1ENPP2CYP1A2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10007142-B2 Dye-based polarizer as well as polarizing plate and liquid crystal display device using the polarizer NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2018-06-26 US disclosed
US-20180074371-A1 DYE-BASED POLARIZER AS WELL AS POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE USING THE POLARIZER POLATECHNO CO., LTD. (JP) 2018-03-15 US disclosed
US-9341747-B2 Azo compound and salt thereof, and dye-based polarizing film and polarizing plate containing the same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2016-05-17 US disclosed
US-20160103362-A1 Azo Compound and Salt Thereof, And Dye-Based Polarizing Film And Polarizing Plate Containing The Same POLATECHNO CO LTD (JP) 2016-04-14 US disclosed
US-9244194-B2 Azo compound and salt thereof, and dye-based polarizing film and polarizing plate containing the same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2016-01-26 US disclosed
US-20150337134-A1 Azo Compound And Salt Thereof, And Dye-Based Polarizing Film And Polarizing Plate Containing The Same NIPPON KAYAKU KK (JP) 2015-11-26 US disclosed
US-20140218797-A1 Polarizing Element And Polarizing Plate POLATECHNO CO., LTD. (JP) 2014-08-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160103362-A1 Azo Compound and Salt Thereof, And Dye-Based Polarizing Film And Polarizing Plate Containing The Same TYR, CRY1, NAP1L4 ATIC 3076/4885CTRB1 3950/4885SUMO2 3302/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.