SCHEMBL15935141

SCHEMBL15935141

COc1ccc(N=Nc2ccc3c(O)c(N=Nc4cc(C)c(N=Nc5ccc(N=Nc6ccc(N=Nc7cc8c(S(=O)(=O)O)cccc8cc7S(=O)(=O)O)c(C)c6)c(C)c5)cc4C)ccc3c2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.48
KMT2A Q03164 5/20 0.48
NPC1 O15118 3/20 0.48
RAB9A P51151 3/20 0.48
ATIC P31939 3/20 0.46
L3MBTL1 Q9Y468 2/20 0.45
ENPP2 Q13822 7/20 0.44
CTRB1 P17538 1/20 0.43
SUMO2 P61956 1/20 0.42
SUMO1 P63165 1/20 0.42
SENP7 Q9BQF6 1/20 0.42
SENP2 Q9HC62 1/20 0.42
CYP1A2 P05177 1/20 0.41
MPL P40238 1/20 0.40
CTRC Q99895 1/20 0.40
BRD4 O60885 1/20 0.40
ALDH1A1 P00352 2/20 0.39
HIF1A Q16665 1/20 0.39
POLB P06746 1/20 0.39
HSP90AA1 P07900 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15935104 0.92 ENPP2 (0.47) MEN1KMT2ANPC1RAB9AATIC
SCHEMBL15935113 0.91 ATIC (0.48) MEN1KMT2ANPC1RAB9AATIC
SCHEMBL15935111 0.91 ATIC (0.48) MEN1KMT2ANPC1RAB9AATIC
SCHEMBL15935143 0.90 BRD4 (0.51) MEN1KMT2ANPC1RAB9AATIC
SCHEMBL15935106 0.90 ENPP2 (0.47) MEN1KMT2ANPC1RAB9AATIC
SCHEMBL17460875 0.90 ATIC (0.46) MEN1KMT2ANPC1RAB9AATIC
SCHEMBL17460863 0.89 ATIC (0.52) MEN1KMT2ANPC1RAB9AATIC
SCHEMBL15935147 0.89 ATIC (0.51) MEN1KMT2ANPC1RAB9AATIC
SCHEMBL17280503 0.88 ENPP2 (0.53) MEN1KMT2ANPC1RAB9AATIC
SCHEMBL15935120 0.88 ENPP2 (0.53) MEN1KMT2ANPC1RAB9AATIC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10007142-B2 Dye-based polarizer as well as polarizing plate and liquid crystal display device using the polarizer NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2018-06-26 US disclosed
US-20180074371-A1 DYE-BASED POLARIZER AS WELL AS POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE USING THE POLARIZER POLATECHNO CO., LTD. (JP) 2018-03-15 US disclosed
US-20140218797-A1 Polarizing Element And Polarizing Plate POLATECHNO CO., LTD. (JP) 2014-08-07 US disclosed