Ethylene Glycol

Ethylene Glycol

SCHEMBL1593589

CCC(=O)ON1C(=O)CCC1=O.OCCO

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
CYP1A2 P05177 1/20 0.35
HPGD P15428 1/20 0.35
CYP2C19 P33261 1/20 0.35
BLM P54132 1/20 0.35
WRN Q14191 1/20 0.35
HIF1A Q16665 1/20 0.35
ADORA3 P0DMS8 1/20 0.33
ADORA2A P29274 1/20 0.33
ADORA2B P29275 1/20 0.33
PSMB8 P28062 1/20 0.32
PSMB5 P28074 1/20 0.32
CHRM2 P08172 1/20 0.32
CHRM4 P08173 1/20 0.32
CHRM1 P11229 1/20 0.32
CHRM3 P20309 1/20 0.32
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
GAA P10253 1/20 0.31
MGLL Q99685 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethylene Glycol SCHEMBL4555859 1.00 ALDH1A1 (0.35) ALDH1A1CYP1A2HPGDCYP2C19BLM
Propionic Acid SCHEMBL28906123 0.95 FFAR3 (0.34) ALDH1A1CYP1A2HPGDCYP2C19BLM
SCHEMBL17756748 0.94 ALDH1A1 (0.38) ALDH1A1CYP1A2HPGDCYP2C19BLM
SCHEMBL30474637 0.94 ALDH1A1 (0.38) ALDH1A1CYP1A2HPGDCYP2C19BLM
SCHEMBL57077 0.94 ALDH1A1 (0.38) ALDH1A1CYP1A2HPGDCYP2C19BLM
Sulfuric Acid SCHEMBL28284052 0.87 MGLL (0.34) ALDH1A1CYP1A2HPGDCYP2C19BLM
Ethylene Glycol SCHEMBL28215416 0.85 ALDH1A1 (0.39) ALDH1A1ADORA3ADORA2AADORA2BPSMB8
Acetonitrile SCHEMBL27805140 0.85 ALDH1A1 (0.33) ALDH1A1CYP1A2HPGDCYP2C19BLM
Ethylene Glycol SCHEMBL999673 0.84 PSMB8 (0.36) PSMB8PSMB5MGLL
Ethylene Glycol SCHEMBL15201496 0.82 KMT2A (0.43) PSMB8PSMB5KMT2ASMN1; SMN2PRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104046600-B The new application of multi-arm polyethylene glycol dressing agent and its application in modification L-Asparaginasum 江苏众红生物工程创药研究院有限公司 2019-04-05 CN claimed
CN-108379561-A A kind of PEGylated uricoxidase freeze dried powder and preparation method thereof 修正生物医药(杭州)研究院有限公司 2018-08-10 CN claimed
CN-106632650-A Ciliary neurotrophic factor mutant and modified mutant and application thereof 北京生物制品研究所有限责任公司 2017-05-10 CN claimed
CN-106632651-A ciliary neurotrophic factor mutant, modified ciliary neurotrophic factor mutant, and applications of ciliary neurotrophic factor mutant and modified ciliary neurotrophic factor mutant 北京生物制品研究所有限责任公司 2017-05-10 CN claimed
CN-103184209-B Human arginase and Pegylation human arginase and application thereof Biozone (Shanghai) limited biological technology (CN) 2015-09-16 CN claimed
US-20060258560-A1 Dry tissue sealant compositions FIBROGEN, INC. 2006-11-16 US claimed
EP-1585758-A4 PEPTIDES HAVING PROTECTED AMINES OF UNTARGETED SITES, METHODS FOR PRODUCTION THEREOF AND OF SPECIFICALLY CONJUGATED PEG PEPTIDES USING THE SAME PEGSPHERE CO LTD (KR) 2006-06-07 EP claimed
EP-1585758-A1 PEPTIDES HAVING PROTECTED AMINES OF UNTARGETED SITES, METHODS FOR PRODUCTION THEREOF AND OF SPECIFICALLY CONJUGATED PEG PEPTIDES USING THE SAME PEGSPHERE Co., Ltd. (KR) 2005-10-19 EP claimed
WO-2004065412-A1 PEPTIDES HAVING PROTECTED AMINES OF UNTARGETED SITES, METHODS FOR PRODUCTION THEREOF AND OF SPECIFICALLY CONJUGATED PEG PEPTIDES USING THE SAME PEGSPHERE CO., LTD. (KR) 2004-08-05 WO claimed
WO-2004028404-A2 DRY TISSUE SEALANT COMPOSITIONS FIBROGEN, INC. (US) 2004-04-08 WO claimed
WO-2024091863-A1 COMBINATORIAL, AND ROTATIONAL COMBINATORIAL THERAPIES FOR OBESITY AND OTHER DISEASES STARROCK PHARMA LLC (US) 2024-05-02 WO disclosed
CN-116056720-A Methods of treating viral infections using arginase 香港商康达医药科技有限公司 2023-05-02 CN disclosed
CN-113831529-A Preparation method of monomethoxy polyethylene glycol carboxylic acid and functional derivative thereof 江苏众红生物工程创药研究院有限公司 2021-12-24 CN disclosed
CN-104046600-B The new application of multi-arm polyethylene glycol dressing agent and its application in modification L-Asparaginasum 江苏众红生物工程创药研究院有限公司 2019-04-05 CN disclosed
CN-104558148-B Ciliary nerve trophic factor mutant and its modification type mutant and purposes 北京生物制品研究所有限责任公司 2018-11-06 CN disclosed
US-20050176076-A1 Multiplex protease profiling APPLERA CORPORATION 2005-08-11 US disclosed
WO-2005066359-A1 MULTIPLEX PROTEASE PROFILING APPLERA CORPORATION (US) 2005-07-21 WO disclosed
WO-2004091494-A2 METHOD FOR PREPARATION OF SITE-SPECIFIC PROTEIN CONJUGATES PR PHARMACEUTICALS INC. (US) 2004-10-28 WO disclosed
WO-2004065412-A1 PEPTIDES HAVING PROTECTED AMINES OF UNTARGETED SITES, METHODS FOR PRODUCTION THEREOF AND OF SPECIFICALLY CONJUGATED PEG PEPTIDES USING THE SAME PEGSPHERE CO., LTD. (KR) 2004-08-05 WO disclosed
WO-2004028404-A2 DRY TISSUE SEALANT COMPOSITIONS FIBROGEN, INC. (US) 2004-04-08 WO disclosed