Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | WRN | Q14191 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene Glycol SCHEMBL4555859 | 1.00 | ALDH1A1 (0.35) | ALDH1A1CYP1A2HPGDCYP2C19BLM | |
| Propionic Acid SCHEMBL28906123 | 0.95 | FFAR3 (0.34) | ALDH1A1CYP1A2HPGDCYP2C19BLM | |
| SCHEMBL17756748 | 0.94 | ALDH1A1 (0.38) | ALDH1A1CYP1A2HPGDCYP2C19BLM | |
| SCHEMBL30474637 | 0.94 | ALDH1A1 (0.38) | ALDH1A1CYP1A2HPGDCYP2C19BLM | |
| SCHEMBL57077 | 0.94 | ALDH1A1 (0.38) | ALDH1A1CYP1A2HPGDCYP2C19BLM | |
| Sulfuric Acid SCHEMBL28284052 | 0.87 | MGLL (0.34) | ALDH1A1CYP1A2HPGDCYP2C19BLM | |
| Ethylene Glycol SCHEMBL28215416 | 0.85 | ALDH1A1 (0.39) | ALDH1A1ADORA3ADORA2AADORA2BPSMB8 | |
| Acetonitrile SCHEMBL27805140 | 0.85 | ALDH1A1 (0.33) | ALDH1A1CYP1A2HPGDCYP2C19BLM | |
| Ethylene Glycol SCHEMBL999673 | 0.84 | PSMB8 (0.36) | PSMB8PSMB5MGLL | |
| Ethylene Glycol SCHEMBL15201496 | 0.82 | KMT2A (0.43) | PSMB8PSMB5KMT2ASMN1; SMN2PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104046600-B | The new application of multi-arm polyethylene glycol dressing agent and its application in modification L-Asparaginasum | 江苏众红生物工程创药研究院有限公司 | 2019-04-05 | — | — | CN | claimed |
| CN-108379561-A | A kind of PEGylated uricoxidase freeze dried powder and preparation method thereof | 修正生物医药(杭州)研究院有限公司 | 2018-08-10 | — | — | CN | claimed |
| CN-106632650-A | Ciliary neurotrophic factor mutant and modified mutant and application thereof | 北京生物制品研究所有限责任公司 | 2017-05-10 | — | — | CN | claimed |
| CN-106632651-A | ciliary neurotrophic factor mutant, modified ciliary neurotrophic factor mutant, and applications of ciliary neurotrophic factor mutant and modified ciliary neurotrophic factor mutant | 北京生物制品研究所有限责任公司 | 2017-05-10 | — | — | CN | claimed |
| CN-103184209-B | Human arginase and Pegylation human arginase and application thereof | Biozone (Shanghai) limited biological technology (CN) | 2015-09-16 | — | — | CN | claimed |
| US-20060258560-A1 | Dry tissue sealant compositions | FIBROGEN, INC. | 2006-11-16 | — | — | US | claimed |
| EP-1585758-A4 | PEPTIDES HAVING PROTECTED AMINES OF UNTARGETED SITES, METHODS FOR PRODUCTION THEREOF AND OF SPECIFICALLY CONJUGATED PEG PEPTIDES USING THE SAME | PEGSPHERE CO LTD (KR) | 2006-06-07 | — | — | EP | claimed |
| EP-1585758-A1 | PEPTIDES HAVING PROTECTED AMINES OF UNTARGETED SITES, METHODS FOR PRODUCTION THEREOF AND OF SPECIFICALLY CONJUGATED PEG PEPTIDES USING THE SAME | PEGSPHERE Co., Ltd. (KR) | 2005-10-19 | — | — | EP | claimed |
| WO-2004065412-A1 | PEPTIDES HAVING PROTECTED AMINES OF UNTARGETED SITES, METHODS FOR PRODUCTION THEREOF AND OF SPECIFICALLY CONJUGATED PEG PEPTIDES USING THE SAME | PEGSPHERE CO., LTD. (KR) | 2004-08-05 | — | — | WO | claimed |
| WO-2004028404-A2 | DRY TISSUE SEALANT COMPOSITIONS | FIBROGEN, INC. (US) | 2004-04-08 | — | — | WO | claimed |
| WO-2024091863-A1 | COMBINATORIAL, AND ROTATIONAL COMBINATORIAL THERAPIES FOR OBESITY AND OTHER DISEASES | STARROCK PHARMA LLC (US) | 2024-05-02 | — | — | WO | disclosed |
| CN-116056720-A | Methods of treating viral infections using arginase | 香港商康达医药科技有限公司 | 2023-05-02 | — | — | CN | disclosed |
| CN-113831529-A | Preparation method of monomethoxy polyethylene glycol carboxylic acid and functional derivative thereof | 江苏众红生物工程创药研究院有限公司 | 2021-12-24 | — | — | CN | disclosed |
| CN-104046600-B | The new application of multi-arm polyethylene glycol dressing agent and its application in modification L-Asparaginasum | 江苏众红生物工程创药研究院有限公司 | 2019-04-05 | — | — | CN | disclosed |
| CN-104558148-B | Ciliary nerve trophic factor mutant and its modification type mutant and purposes | 北京生物制品研究所有限责任公司 | 2018-11-06 | — | — | CN | disclosed |
| US-20050176076-A1 | Multiplex protease profiling | APPLERA CORPORATION | 2005-08-11 | — | — | US | disclosed |
| WO-2005066359-A1 | MULTIPLEX PROTEASE PROFILING | APPLERA CORPORATION (US) | 2005-07-21 | — | — | WO | disclosed |
| WO-2004091494-A2 | METHOD FOR PREPARATION OF SITE-SPECIFIC PROTEIN CONJUGATES | PR PHARMACEUTICALS INC. (US) | 2004-10-28 | — | — | WO | disclosed |
| WO-2004065412-A1 | PEPTIDES HAVING PROTECTED AMINES OF UNTARGETED SITES, METHODS FOR PRODUCTION THEREOF AND OF SPECIFICALLY CONJUGATED PEG PEPTIDES USING THE SAME | PEGSPHERE CO., LTD. (KR) | 2004-08-05 | — | — | WO | disclosed |
| WO-2004028404-A2 | DRY TISSUE SEALANT COMPOSITIONS | FIBROGEN, INC. (US) | 2004-04-08 | — | — | WO | disclosed |