Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 6/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL70665 | 0.94 | ALDH1A1 (0.43) | ALDH1A1PSMB8PSMB5KMT2ASMN1; SMN2 | |
| Ethylene Glycol SCHEMBL15201496 | 0.90 | KMT2A (0.43) | PSMB8PSMB5KMT2ASMN1; SMN2PRKCA | |
| Ethylene Glycol SCHEMBL999673 | 0.89 | PSMB8 (0.36) | PSMB8PSMB5 | |
| Butyric Acid SCHEMBL28354890 | 0.88 | FFAR3 (0.45) | ALDH1A1PSMB8PSMB5KMT2ASMN1; SMN2 | |
| SCHEMBL22171333 | 0.87 | ALDH1A1 (0.40) | ALDH1A1PSMB8PSMB5KMT2ASMN1; SMN2 | |
| Ethylene Glycol SCHEMBL4555859 | 0.85 | ALDH1A1 (0.35) | ALDH1A1PSMB8PSMB5KMT2ASMN1; SMN2 | |
| Ethylene Glycol SCHEMBL1593589 | 0.85 | ALDH1A1 (0.35) | ALDH1A1PSMB8PSMB5KMT2ASMN1; SMN2 | |
| Ethylene Glycol SCHEMBL6523939 | 0.85 | PSMB8 (0.34) | PSMB8PSMB5KMT2ASMN1; SMN2PRKCA | |
| SCHEMBL2607886 | 0.85 | PSMB8 (0.38) | PSMB8PSMB5 | |
| Maleic Acid SCHEMBL28377678 | 0.85 | HCAR2 (0.36) | ALDH1A1PSMB8PSMB5KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110251731-A | A kind of used in tissue engineering islet cells micro-capsule and preparation method thereof | 山东百多安医疗器械有限公司 | 2019-09-20 | — | — | CN | claimed |
| CN-110201234-A | A kind of used in tissue engineering prostatic cell micro-capsule and preparation method thereof | 山东百多安医疗器械有限公司 | 2019-09-06 | — | — | CN | claimed |
| CN-105802947-B | Polyethylene glycol modified protein and the method for modified outcome purifying | 江苏众红生物工程创药研究院有限公司 | 2019-11-19 | — | — | CN | disclosed |
| CN-110251731-A | A kind of used in tissue engineering islet cells micro-capsule and preparation method thereof | 山东百多安医疗器械有限公司 | 2019-09-20 | — | — | CN | disclosed |
| CN-110201234-A | A kind of used in tissue engineering prostatic cell micro-capsule and preparation method thereof | 山东百多安医疗器械有限公司 | 2019-09-06 | — | — | CN | disclosed |
| CN-105796507-B | Pharmaceutical composition and preparation method thereof containing Pegaspargase | 江苏众红生物工程创药研究院有限公司 | 2019-01-18 | — | — | CN | disclosed |
| CN-108893454-A | Polyethyleneglycol modified recombination glutathione peroxidase GPx1 mutant, preparation method and anti-oxidant application | 吉林大学 | 2018-11-27 | — | — | CN | disclosed |
| CN-108064282-A | Adenosine deaminase -2 (ADA2), its variant composition and use its method | 哈洛齐梅公司 | 2018-05-22 | — | — | CN | disclosed |
| CN-107753953-A | The preparation of Pegylation kininogenase and its application | 江苏众红生物工程创药研究院有限公司 | 2018-03-06 | — | — | CN | disclosed |
| CN-107760661-A | PEG trims of medicinal kininogenase and its preparation method and application | 江苏众红生物工程创药研究院有限公司 | 2018-03-06 | — | — | CN | disclosed |