Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30074410 | 1.00 | ALDH1A1 (0.46) | ALDH1A1NQO2TAAR1CYP1A1CYP1B1 | |
| SCHEMBL388181 | 0.82 | ALDH1A1 (0.69) | ALDH1A1NQO2CYP1A1CYP1B1CYP3A4 | |
| SCHEMBL168353 | 0.82 | ALDH1A1 (0.69) | ALDH1A1NQO2TAAR1CYP1A1CYP1B1 | |
| SCHEMBL186502 | 0.82 | ALDH1A1 (0.59) | ALDH1A1NQO2TAAR1CYP1A1CYP1B1 | |
| SCHEMBL811852 | 0.82 | ALDH1A1 (0.59) | ALDH1A1NQO2CYP1A1CYP1B1CYP3A4 | |
| SCHEMBL2227610 | 0.76 | KAT6A (0.35) | ALDH1A1FFAR4NPC1RAB9ARELA | |
| SCHEMBL21577485 | 0.76 | — | — | |
| SCHEMBL2225192 | 0.76 | FGFR1 (0.41) | CYP3A4NPC1APP | |
| SCHEMBL11885 | 0.73 | ALDH1A1 (0.48) | ALDH1A1NQO2TAAR1CYP1A1CYP1B1 | |
| SCHEMBL388119 | 0.73 | ALDH1A1 (0.48) | ALDH1A1CYP1A1CYP1B1CYP3A4CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240246969-A1 | HETEROCYCLIC DERIVATIVES AS CAMKK2 INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY | 2024-07-25 | — | — | US | disclosed |
| EP-4337660-A1 | HETEROCYCLIC DERIVATIVES AS CAMKK2 INHIBITORS | Bristol-Myers Squibb Company (US) | 2024-03-20 | — | — | EP | disclosed |
| CN-117597345-A | Heterocyclic derivatives as CaMKK2 inhibitors | 百时美施贵宝公司 | 2024-02-23 | — | — | CN | disclosed |
| US-20220017499-A1 | Process for Preparing 1-([3R,4S)-4-Cyanotetrahydropyran-3-YL]-3-[(2-fluoro-6-Methoxy-4-Pyridyl)Amino]Pyrazole-4-Carboxamide | INTERVET INC. (US) | 2022-01-20 | — | — | US | disclosed |
| EP-3223822-B1 | BILE ACID DERIVATIVES AS FXR/TGR5 AGONISTS | ENANTA PHARM INC (US) | 2020-07-01 | — | — | EP | disclosed |
| EP-2516445-B1 | TRICYCLIC DERIVATIVES AND THEIR PHARMACEUTICAL USE AND COMPOSITIONS | CEPHALON INC (US) | 2015-03-11 | — | — | EP | disclosed |
| EP-2792678-A1 | Tricyclic derivatives and their pharmaceutical use and compositions | CEPHALON, INC. (US) | 2014-10-22 | — | — | EP | disclosed |
| EP-2516446-B1 | SUBSTITUTED HEXAHYDROCHROMENO[3,4-B]PYRROLES WITH AFFINITY FOR THE SEROTONIN RECEPTOR (5-HT) FAMILY | CEPHALON INC (US) | 2014-08-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240246969-A1 | HETEROCYCLIC DERIVATIVES AS CAMKK2 INHIBITORS | CAMKK2, CAMKK1, CAMK1 | ALDH1A1 3614/4885NQO2 2672/4885TAAR1 4087/4885 |
| US-20220017499-A1 | Process for Preparing 1-([3R,4S)-4-Cyanotetrahydropyran-3-YL]-3-[(2-fluoro-6-Methoxy-4-Pyridyl)Amino]Pyrazole-4-Carboxamide | CYP4B1, CYP3A4, CYP4F3 | ALDH1A1 473/4885NQO2 690/4885TAAR1 867/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.