Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.34 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9919101 | 0.77 | BRD9 (0.40) | L3MBTL1KDM4ETGFBR1NPC1RAB9A | |
| SCHEMBL15680577 | 0.73 | L3MBTL1 (0.50) | L3MBTL1IP6K1KDM4EACVR1ALDH1A1 | |
| SCHEMBL21892099 | 0.71 | L3MBTL1 (0.46) | L3MBTL1IP6K1KDM4EACVR1ALDH1A1 | |
| SCHEMBL4728366 | 0.70 | HDAC6 (0.59) | L3MBTL1IP6K1KDM4EACVR1ALDH1A1 | |
| SCHEMBL4560336 | 0.70 | ALDH1A1 (0.50) | L3MBTL1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL12351357 | 0.69 | L3MBTL1 (0.47) | L3MBTL1IP6K1KDM4EACVR1ALDH1A1 | |
| SCHEMBL12342255 | 0.69 | L3MBTL1 (0.47) | L3MBTL1IP6K1KDM4EACVR1ALDH1A1 | |
| SCHEMBL18404755 | 0.69 | PARP1 (0.46) | IP6K1ALDH1A1 | |
| SCHEMBL29607244 | 0.68 | L3MBTL1 (0.60) | L3MBTL1IP6K1KDM4EACVR1ALDH1A1 | |
| SCHEMBL7600132 | 0.68 | L3MBTL1 (0.60) | L3MBTL1IP6K1KDM4EACVR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9655363-B2 | Microbiocides | SYNGENTA PARTICIPATIONS AG (CH) | 2017-05-23 | — | — | US | disclosed |
| US-9655363-B2 | Microbiocides | SYNGENTA PARTICIPATIONS AG (CH) | 2017-05-23 | — | — | US | disclosed |
| EP-2951167-B1 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-01-25 | — | — | EP | disclosed |
| US-20150351402-A1 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-12-10 | — | — | US | disclosed |
| US-20150351402-A1 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-12-10 | — | — | US | disclosed |
| WO-2014118170-A1 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2014-08-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150351402-A1 | NOVEL MICROBIOCIDES | MSR1, C1R, CD14 | L3MBTL1 644/4885IP6K1 3379/4885KDM4E 2080/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.