Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 2/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 2/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15910526 | 0.84 | HTT (0.47) | ALDH1A1NPC1RAB9AHCRTR1HCRTR2 | |
| SCHEMBL15925145 | 0.79 | TSHR (0.48) | ALDH1A1TSHRNPC1RAB9AEGFR | |
| SCHEMBL21766656 | 0.77 | NAMPT (0.47) | ALDH1A1TSHRNPC1RAB9ARORC | |
| SCHEMBL19151107 | 0.74 | TYK2 (0.50) | ALDH1A1NPC1RAB9AGRM5HCRTR1 | |
| SCHEMBL31703164 | 0.74 | ALDH1A1 (0.43) | ALDH1A1EGFRGRM5HCRTR1HCRTR2 | |
| SCHEMBL19116805 | 0.70 | SMN1; SMN2 (0.51) | RAB9AHCRTR1HCRTR2RORCSMN1; SMN2 | |
| SCHEMBL15205400 | 0.70 | GRM5 (0.44) | NPC1RAB9AGRM5HCRTR1HCRTR2 | |
| SCHEMBL3558994 | 0.69 | L3MBTL1 (0.52) | GRM5RORCTYK2 | |
| SCHEMBL14774917 | 0.68 | EGFR (0.48) | ALDH1A1RAB9AEGFRERBB3HCRTR1 | |
| SCHEMBL19404204 | 0.68 | ALDH1A1 (0.41) | ALDH1A1NPC1RAB9AGRM5HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014122065-A1 | 2-AMINOPYRIDINE DERIVATIVES AS PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-08-14 | — | — | WO | disclosed |
| WO-2014122065-A1 | 2-AMINOPYRIDINE DERIVATIVES AS PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-08-14 | — | — | WO | disclosed |