Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | PTPRC | P08575 | 1/20 | 0.43 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21766656 | 0.85 | NAMPT (0.47) | ALDH1A1NPC1RAB9AMAPK8POLB | |
| SCHEMBL15925145 | 0.85 | TSHR (0.48) | ALDH1A1NPC1RAB9AMAPK10MAPK8 | |
| SCHEMBL15940624 | 0.84 | ALDH1A1 (0.44) | ALDH1A1NPC1RAB9AMAPK10MAPK8 | |
| SCHEMBL19151107 | 0.81 | TYK2 (0.50) | ALDH1A1NPC1RAB9AHCRTR1HCRTR2 | |
| SCHEMBL14781048 | 0.81 | MEN1 (0.51) | HTTALDH1A1POLBHPGDHCRTR1 | |
| SCHEMBL15941191 | 0.81 | HPGD (0.56) | HTTALDH1A1NPC1RAB9AMAPK10 | |
| SCHEMBL15910524 | 0.81 | L3MBTL1 (0.56) | HTTALDH1A1NPC1RAB9AMAPK10 | |
| SCHEMBL15940876 | 0.80 | NPC1 (0.45) | HTTALDH1A1NPC1RAB9AMAPK10 | |
| SCHEMBL31703164 | 0.79 | ALDH1A1 (0.43) | HTTALDH1A1HCRTR1HCRTR2SMN1; SMN2 | |
| SCHEMBL15948100 | 0.78 | NPC1 (0.44) | HTTALDH1A1NPC1RAB9AMAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014122065-A1 | 2-AMINOPYRIDINE DERIVATIVES AS PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-08-14 | — | — | WO | disclosed |
| WO-2014122065-A1 | 2-AMINOPYRIDINE DERIVATIVES AS PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-08-14 | — | — | WO | disclosed |
| EP-2762468-A1 | 2-aminopyridine derivatives as plant growth regulating compounds | Syngenta Participations AG. (CH) | 2014-08-06 | — | — | EP | disclosed |
| EP-2762468-A1 | 2-aminopyridine derivatives as plant growth regulating compounds | Syngenta Participations AG. (CH) | 2014-08-06 | — | — | EP | disclosed |