Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15940876 | 0.80 | NPC1 (0.45) | NPC1RAB9ASMN1; SMN2ALDH1A1MAPK10 | |
| SCHEMBL3921965 | 0.80 | IGF1R (0.44) | NR3C2MEN1KMT2A | |
| SCHEMBL28372044 | 0.79 | MAPK14 (0.48) | MAPK14 | |
| SCHEMBL4304915 | 0.77 | NR3C2 (0.41) | SMN1; SMN2ALDH1A1NR3C2KMT2A | |
| SCHEMBL7106525 | 0.76 | IGF1R (0.33) | NR3C2MAPK14MEN1KMT2A | |
| SCHEMBL15994295 | 0.74 | AR (0.45) | NPC1RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL29468748 | 0.74 | AR (0.45) | NPC1RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL15941191 | 0.74 | HPGD (0.56) | NPC1RAB9AALDH1A1MAPK10L3MBTL1 | |
| SCHEMBL15910524 | 0.74 | L3MBTL1 (0.56) | NPC1RAB9AALDH1A1MAPK10L3MBTL1 | |
| SCHEMBL4303917 | 0.73 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014122065-A1 | 2-AMINOPYRIDINE DERIVATIVES AS PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-08-14 | — | — | WO | disclosed |