Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | PTPRC | P08575 | 1/20 | 0.44 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.44 |
| ▸ | RIOK2 | Q9BVS4 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15941191 | 0.82 | HPGD (0.56) | NPC1RAB9AALDH1A1MAPK10L3MBTL1 | |
| SCHEMBL15910524 | 0.82 | L3MBTL1 (0.56) | NPC1RAB9AALDH1A1MAPK10L3MBTL1 | |
| SCHEMBL15940791 | 0.80 | NPC1 (0.39) | NPC1RAB9AALDH1A1SMN1; SMN2MAPK10 | |
| SCHEMBL15948100 | 0.80 | NPC1 (0.44) | NPC1RAB9AALDH1A1SMN1; SMN2MAPK10 | |
| SCHEMBL15910526 | 0.80 | HTT (0.47) | NPC1RAB9AALDH1A1SMN1; SMN2MAPK10 | |
| SCHEMBL15940757 | 0.78 | NPC1 (0.44) | NPC1RAB9AALDH1A1SMN1; SMN2MAPK10 | |
| SCHEMBL29507273 | 0.77 | L3MBTL1 (0.52) | L3MBTL1NR3C2 | |
| SCHEMBL501285 | 0.77 | L3MBTL1 (0.52) | L3MBTL1NR3C2 | |
| SCHEMBL14791574 | 0.77 | GAA (0.65) | NPC1RAB9AALDH1A1SMN1; SMN2HTT | |
| SCHEMBL6952630 | 0.76 | NR3C2 (0.52) | L3MBTL1NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014122065-A1 | 2-AMINOPYRIDINE DERIVATIVES AS PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-08-14 | — | — | WO | disclosed |
| WO-2014122065-A1 | 2-AMINOPYRIDINE DERIVATIVES AS PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-08-14 | — | — | WO | disclosed |