Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | PTPRC | P08575 | 1/20 | 0.45 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15910524 | 0.83 | L3MBTL1 (0.56) | HPGDRIOK2NPC1RAB9AHTT | |
| SCHEMBL1555088 | 0.82 | HPGD (0.54) | HPGDRIOK2EGFRNPC1RAB9A | |
| SCHEMBL15940876 | 0.82 | NPC1 (0.45) | HPGDRIOK2NPC1RAB9AHTT | |
| SCHEMBL15948100 | 0.81 | NPC1 (0.44) | HPGDNPC1RAB9AHTTL3MBTL1 | |
| SCHEMBL15910526 | 0.81 | HTT (0.47) | HPGDNPC1RAB9AHTTL3MBTL1 | |
| SCHEMBL1554419 | 0.80 | RIOK2 (0.57) | RIOK2EGFRNPC1RAB9AL3MBTL1 | |
| SCHEMBL15940757 | 0.80 | NPC1 (0.44) | HPGDNPC1RAB9AHTTL3MBTL1 | |
| SCHEMBL25130701 | 0.79 | RIOK2 (0.53) | RIOK2EGFRNPC1RAB9AL3MBTL1 | |
| SCHEMBL28710197 | 0.79 | RIOK2 (0.53) | RIOK2EGFRNPC1RAB9AMEN1 | |
| SCHEMBL29083759 | 0.79 | TSHR (0.69) | RIOK2L3MBTL1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014122065-A1 | 2-AMINOPYRIDINE DERIVATIVES AS PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-08-14 | — | — | WO | disclosed |
| WO-2014122065-A1 | 2-AMINOPYRIDINE DERIVATIVES AS PLANT GROWTH REGULATING COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-08-14 | — | — | WO | disclosed |