Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROR1 | Q01973 | 1/20 | 0.77 |
| ▸ | MAOB | P27338 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TAS2R31 | P59538 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14242303 | 0.91 | ROR1 (0.91) | ROR1MAOBALDH1A1CYP3A4KDM4E | |
| SCHEMBL13708477 | 0.83 | ROR1 (0.82) | ROR1MAOBALDH1A1CYP3A4KDM4E | |
| SCHEMBL18104369 | 0.82 | ALDH1A1 (0.68) | ROR1MAOBALDH1A1CYP3A4KDM4E | |
| SCHEMBL18104378 | 0.82 | ALDH1A1 (0.68) | ROR1MAOBALDH1A1CYP3A4KDM4E | |
| SCHEMBL18104325 | 0.80 | ALDH1A1 (0.64) | MAOBALDH1A1CYP3A4KDM4EHPGD | |
| SCHEMBL10005479 | 0.76 | BCHE (0.58) | ROR1MAOBALDH1A1CYP3A4KDM4E | |
| SCHEMBL22465616 | 0.76 | ROR1 (0.69) | ROR1ALDH1A1CYP3A4KDM4EHPGD | |
| SCHEMBL25437506 | 0.75 | MAOB (0.74) | ROR1MAOBCYP3A4KDM4EMAPK1 | |
| SCHEMBL5421488 | 0.75 | ROR1 (0.57) | ROR1CYP3A4ABCG2CYP19A1MAPT | |
| SCHEMBL13906136 | 0.74 | CYP1A1 (0.80) | MAOBALDH1A1CYP3A4HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160243132-A1 | METHODS FOR INHIBITING MUSCLE ATROPHY | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2016-08-25 | — | — | US | disclosed |
| US-9295664-B2 | Methods for lowering blood glucose | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2016-03-29 | — | — | US | disclosed |
| US-20140228333-A1 | METHODS FOR INHIBITING MUSCLE ATROPHY | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2014-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160243132-A1 | METHODS FOR INHIBITING MUSCLE ATROPHY | CPT1B, MYOF, TNNC1 | ROR1 4836/4885MAOB 1761/4885ALDH1A1 3806/4885 |
| US-20140228333-A1 | METHODS FOR INHIBITING MUSCLE ATROPHY | CPT1B, MYOF, TNNC1 | ROR1 4836/4885MAOB 1761/4885ALDH1A1 3806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.