SCHEMBL15946382

SCHEMBL15946382

Cc1ccccc1OCOCCOC(=O)c1ccc(OCOCCOC(=O)c2ccccc2C)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 5/20 0.55
TDP1 Q9NUW8 3/20 0.55
MAPT P10636 6/20 0.45
KMT2A Q03164 3/20 0.45
SMN1; SMN2 Q16637 6/20 0.43
RAB9A P51151 5/20 0.43
NPC1 O15118 4/20 0.43
ALDH1A1 P00352 4/20 0.43
MEN1 O00255 2/20 0.43
GAA P10253 1/20 0.43
MAPK1 P28482 2/20 0.42
CYP2D6 P10635 1/20 0.42
CYP19A1 P11511 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
LMNA P02545 2/20 0.42
KDM4E B2RXH2 2/20 0.41
HTT P42858 1/20 0.41
TSHR P16473 2/20 0.40
RXRA P19793 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16981961 0.96 L3MBTL1 (0.52) L3MBTL1TDP1MAPTKMT2ASMN1; SMN2
SCHEMBL17488383 0.82 RAB9A (0.47) L3MBTL1TDP1KMT2ASMN1; SMN2RAB9A
SCHEMBL26338804 0.82 ALDH1A1 (0.40) L3MBTL1TDP1MAPTKMT2ASMN1; SMN2
SCHEMBL9780126 0.79 TDP1 (0.68) L3MBTL1TDP1MAPTKMT2ASMN1; SMN2
SCHEMBL16590831 0.78 L3MBTL1 (0.50) L3MBTL1TDP1MAPTSMN1; SMN2RAB9A
SCHEMBL5021063 0.78 TDP1 (0.56) L3MBTL1TDP1MAPTKMT2ASMN1; SMN2
SCHEMBL29860961 0.77 LMNA (0.61) L3MBTL1TDP1KMT2ASMN1; SMN2RAB9A
SCHEMBL16049266 0.77 TSHR (0.59) L3MBTL1TDP1KMT2ASMN1; SMN2RAB9A
SCHEMBL17797867 0.77 TSHR (0.59) L3MBTL1TDP1KMT2ASMN1; SMN2RAB9A
SCHEMBL8433421 0.77 TSHR (0.59) L3MBTL1TDP1KMT2ASMN1; SMN2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9581728-B2 Retardation film, polarizing plate and liquid crystal display Konica Minolta, Inc. (JP) 2017-02-28 US disclosed
US-9523794-B2 Optical film of cellulose ester and cellulose ether for vertical alignment liquid crystal displays Konica Minolta, Inc. (JP) 2016-12-20 US disclosed
US-20160033684-A1 OPTICAL FILM, POLARIZING PLATE CONTAINING SAME AND VERTICAL ALIGNMENT LIQUID CRYSTAL DISPLAY DEVICE Konica Minolta, Inc. (JP) 2016-02-04 US disclosed
US-20150323703-A1 RETARDATION FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY Konica Minolta, Inc. (JP) 2015-11-12 US disclosed
US-8952600-B2 Circularly polarizing plate and three-dimensional image display apparatus Konica Minolta, Inc. (JP) 2015-02-10 US disclosed
US-20140225499-A1 CIRCULARLY POLARIZING PLATE AND THREE-DIMENSIONAL IMAGE DISPLAY APPARATUS Konica Minolta, Inc. (JP) 2014-08-14 US disclosed