Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.56 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | HPGD | P15428 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30615051 | 0.84 | NPBWR1 (0.78) | NPC1RAB9AGAANPBWR1DGAT1 | |
| SCHEMBL29091542 | 0.84 | NPBWR1 (0.78) | NPC1RAB9AGAANPBWR1DGAT1 | |
| SCHEMBL13118022 | 0.84 | HDAC6 (0.68) | NPC1RAB9AGAANPBWR1DGAT1 | |
| Ammonia Solution, Strong SCHEMBL2446708 | 0.83 | HDAC6 (0.66) | NPC1RAB9AGAANPBWR1DGAT1 | |
| SCHEMBL15245160 | 0.82 | DGAT1 (0.79) | NPC1RAB9AGAANPBWR1DGAT1 | |
| SCHEMBL2324234 | 0.79 | NPC1 (0.62) | NPC1RAB9AGAANPBWR1HDAC6 | |
| SCHEMBL10576078 | 0.79 | HDAC6 (0.52) | NPC1RAB9AGAANPBWR1DGAT1 | |
| SCHEMBL22649095 | 0.78 | NPC1 (0.67) | NPC1RAB9AGAANPBWR1DGAT1 | |
| SCHEMBL3132123 | 0.76 | NPC1 (0.68) | NPC1RAB9AGAANPBWR1DGAT1 | |
| SCHEMBL2091998 | 0.76 | NPC1 (0.62) | NPC1RAB9AGAANPBWR1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140227207-A1 | COSMETIC COMPOSITIONS CONTAINING SUBSTITUTED AZOLE AND METHODS FOR ALLEVIATING THE SIGNS OF PHOTOAGED SKIN | THE PROCTER & GAMBLE COMPANY (US) | 2014-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140227207-A1 | COSMETIC COMPOSITIONS CONTAINING SUBSTITUTED AZOLE AND METHODS FOR ALLEVIATING THE SIGNS OF PHOTOAGED SKIN | TYR, CUTA, CDKN1A | NPC1 3494/4885RAB9A 4463/4885GAA 1079/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.