Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | APEX1 | P27695 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9448477 | 0.83 | ALDH1A1 (0.45) | ALDH1A1TDP1LMNAAPEX1RECQL | |
| SCHEMBL10099684 | 0.76 | ALDH1A1 (0.47) | ALDH1A1TDP1LMNAAPEX1RECQL | |
| SCHEMBL11339493 | 0.73 | LMNA (0.46) | ALDH1A1TDP1LMNAAPEX1RECQL | |
| SCHEMBL11348296 | 0.73 | ALDH1A1 (0.44) | ALDH1A1TDP1LMNAAPEX1RECQL | |
| SCHEMBL13888468 | 0.73 | ALDH1A1 (0.44) | ALDH1A1TDP1LMNAAPEX1RECQL | |
| SCHEMBL201849 | 0.73 | ALDH1A1 (0.51) | ALDH1A1TDP1LMNAAPEX1RECQL | |
| SCHEMBL13888467 | 0.73 | ALDH1A1 (0.50) | ALDH1A1TDP1LMNAAPEX1RECQL | |
| SCHEMBL14461718 | 0.71 | ALDH1A1 (0.44) | ALDH1A1TDP1LMNAAPEX1RECQL | |
| SCHEMBL4107319 | 0.71 | KMT2A (0.47) | ALDH1A1TDP1LMNAAPEX1RECQL | |
| SCHEMBL17843609 | 0.71 | ALDH1A1 (0.44) | ALDH1A1TDP1LMNAAPEX1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140227212-A1 | POLYMERIZED SUNSCREEN ABSORBERS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2014-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140227212-A1 | POLYMERIZED SUNSCREEN ABSORBERS | PCNA, MCM3, SYMPK | ALDH1A1 2364/4885TDP1 2017/4885LMNA 1271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.