Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.32 |
| ▸ | HTR3B | O95264 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.32 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | GUSB | P08236 | 1/20 | 0.31 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 2/20 | 0.31 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15948289 | 0.93 | CHRNB2 (0.34) | CHRNB2CHRNA4ADRB1GUSB | |
| SCHEMBL15875839 | 0.88 | ADRB1 (0.35) | ADRB1HTR1AHTR3EHTR3BHTR3A | |
| SCHEMBL14057824 | 0.84 | ABHD6 (0.31) | CHRNB2CHRNA4ADRB1HTR1AHTR1D | |
| SCHEMBL15948243 | 0.81 | CHRNB2 (0.34) | CHRNB2CHRNA4ADRB1HTR1DHTR3E | |
| SCHEMBL15909115 | 0.81 | TDP1 (0.33) | ADRB1HTR1AGUSBALDH1A1MAPT | |
| SCHEMBL15925816 | 0.80 | ADRB1 (0.41) | ADRB1HTR1AHTR1DHTR1BHTR3E | |
| SCHEMBL15948217 | 0.78 | — | — | |
| SCHEMBL18913258 | 0.77 | ADRB1 (0.41) | ADRB1HTR1AHTR1DHTR1BHTR3E | |
| SCHEMBL15875850 | 0.77 | — | — | |
| SCHEMBL15875878 | 0.77 | CHRNB2 (0.37) | CHRNB2CHRNA4ADRB1HTR1AGUSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8809317-B2 | Antiviral compounds | PROSETTA ANTIVIRAL INC. (US) | 2014-08-19 | — | — | US | claimed |