Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.31 |
| ▸ | HTR3B | O95264 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.31 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15948289 | 0.86 | CHRNB2 (0.34) | CHRNB2CHRNA4ADRB1 | |
| SCHEMBL15948223 | 0.84 | CRHR1 (0.35) | SLC6A2SLC6A4MAPT | |
| SCHEMBL15875978 | 0.82 | ADRB1 (0.43) | ADRB1HTR3EHTR3BALDH1A1HTR1D | |
| SCHEMBL15948246 | 0.81 | CHRNB2 (0.34) | CHRNB2CHRNA4ADRB1HTR3EHTR3B | |
| SCHEMBL15948197 | 0.81 | CRHR1 (0.40) | MAPT | |
| SCHEMBL14057824 | 0.80 | ABHD6 (0.31) | CHRNB2CHRNA4ADRB1HTR1D | |
| SCHEMBL12813221 | 0.77 | IDH1 (0.31) | — | |
| SCHEMBL15875878 | 0.76 | CHRNB2 (0.37) | CHRNB2CHRNA4ADRB1SLC6A2SLC6A4 | |
| SCHEMBL12813227 | 0.75 | ACVR1 (0.32) | HTR3EHTR3BALDH1A1HTR1DHTR2C | |
| SCHEMBL15909115 | 0.74 | TDP1 (0.33) | ADRB1ALDH1A1HTR2CMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8809317-B2 | Antiviral compounds | PROSETTA ANTIVIRAL INC. (US) | 2014-08-19 | — | — | US | claimed |