Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1594228 | 0.84 | ALDH1A1 (0.59) | MITFALDH1A1PKMMAPTKMT2A | |
| SCHEMBL27708092 | 0.82 | ALDH1A1 (0.41) | MITFALDH1A1PKMKMT2ALMNA | |
| SCHEMBL1080487 | 0.81 | MITF (0.54) | MITFALDH1A1PKMMAPTKMT2A | |
| SCHEMBL2570796 | 0.81 | MITF (0.49) | MITFALDH1A1ARPKMMAPT | |
| SCHEMBL30211422 | 0.80 | MITF (0.56) | MITFALDH1A1PKMMAPTKMT2A | |
| SCHEMBL1594682 | 0.80 | LMNA (0.45) | ALDH1A1MAPTKMT2ALMNAJAK2 | |
| SCHEMBL31614495 | 0.79 | MITF (0.52) | MITFALDH1A1PKMMAPTKMT2A | |
| SCHEMBL1594419 | 0.78 | MITF (0.52) | MITFALDH1A1ARPKMMAPT | |
| SCHEMBL23389306 | 0.77 | ALDH1A1 (0.64) | MITFALDH1A1PKMKMT2ALMNA | |
| Hydrochloric Acid SCHEMBL5741754 | 0.77 | MITF (0.51) | MITFALDH1A1ARPKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2755964-B1 | SULFONIC ACID SALTS OF HETEROCYCLYLAMIDE-SUBSTITUTED IMIDAZOLES | AICURIS ANTI INFECTIVE CURES GMBH (DE) | 2016-06-22 | — | — | EP | disclosed |
| US-9133165-B2 | Sulfonic acid salts of heterocyclylamide-substituted imidazoles | AICURIS GMBH & CO. KG (DE) | 2015-09-15 | — | — | US | disclosed |
| US-9133165-B2 | Sulfonic acid salts of heterocyclylamide-substituted imidazoles | AICURIS GMBH & CO. KG (DE) | 2015-09-15 | — | — | US | disclosed |
| US-9133165-B2 | Sulfonic acid salts of heterocyclylamide-substituted imidazoles | AICURIS GMBH & CO. KG (DE) | 2015-09-15 | — | — | US | disclosed |
| US-20140315924-A1 | SULFONIC ACID SALTS OF HETEROCYCLYLAMIDE-SUBSTITUTED IMIDAZOLES | AICURIS GMBH & CO. KG (DE) | 2014-10-23 | — | — | US | disclosed |
| US-20140315924-A1 | SULFONIC ACID SALTS OF HETEROCYCLYLAMIDE-SUBSTITUTED IMIDAZOLES | AICURIS GMBH & CO. KG (DE) | 2014-10-23 | — | — | US | disclosed |
| US-20140315924-A1 | SULFONIC ACID SALTS OF HETEROCYCLYLAMIDE-SUBSTITUTED IMIDAZOLES | AICURIS GMBH & CO. KG (DE) | 2014-10-23 | — | — | US | disclosed |
| WO-2013037812-A1 | SULFONIC ACID SALTS OF HETEROCYCLYLAMIDE-SUBSTITUTED IMIDAZOLES | AICURIS GMBH & CO. KG (DE) | 2013-03-21 | — | — | WO | disclosed |
| EP-1732901-B1 | ANTIVIRAL 4-AMINOCARBONYLAMINO-SUBSTITUTED IMIDAZOLE COMPOUND | AICURIS GMBH & CO KG (DE) | 2011-11-02 | — | — | EP | disclosed |
| US-7919489-B2 | e.g. 4-({[(4-Chloro-2-methylphenyl)amino]carbonyl}amino)-1-(cyclopropylmethyl)-1H-imidazole-2-carboxylic acid; antiviral agents, especially against cytomegaloviruses and other Herpes viridae; side effect reduction; antibiotic resistance | AICURIS GMBH & CO. KG (DE) | 2011-04-05 | — | — | US | disclosed |
| US-7767704-B2 | Antiviral 4-aminocarbonylamino-substituted imidazole compounds | AICURIS GMBH & CO. KG (DE) | 2010-08-03 | — | — | US | disclosed |
| US-7767704-B2 | Antiviral 4-aminocarbonylamino-substituted imidazole compounds | AICURIS GMBH & CO. KG (DE) | 2010-08-03 | — | — | US | disclosed |
| US-7767704-B2 | Antiviral 4-aminocarbonylamino-substituted imidazole compounds | AICURIS GMBH & CO. KG (DE) | 2010-08-03 | — | — | US | disclosed |
| EP-1853582-B1 | HETEROCYCLYLAMIDE-SUBSTITUTED IMIDAZOLES | AICURIS GMBH & CO KG (DE) | 2009-10-21 | — | — | EP | disclosed |
| US-20080176859-A1 | HETEROCYCLYAMIDE-SUBSTITUTED IMIDAZOLES | AICURIS GMBH & CO. KG (DE) | 2008-07-24 | — | — | US | disclosed |
| US-20080176859-A1 | HETEROCYCLYAMIDE-SUBSTITUTED IMIDAZOLES | AICURIS GMBH & CO. KG (DE) | 2008-07-24 | — | — | US | disclosed |
| US-20080176859-A1 | HETEROCYCLYAMIDE-SUBSTITUTED IMIDAZOLES | AICURIS GMBH & CO. KG (DE) | 2008-07-24 | — | — | US | disclosed |
| US-20080004275-A1 | Antiviral 4-Aminocarbonylamino-Substituted Imidazole Compounds | BAYER HEALTHCARE AG (DE) | 2008-01-03 | — | — | US | disclosed |
| US-20080004275-A1 | Antiviral 4-Aminocarbonylamino-Substituted Imidazole Compounds | BAYER HEALTHCARE AG (DE) | 2008-01-03 | — | — | US | disclosed |
| US-20080004275-A1 | Antiviral 4-Aminocarbonylamino-Substituted Imidazole Compounds | BAYER HEALTHCARE AG (DE) | 2008-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080176859-A1 | HETEROCYCLYAMIDE-SUBSTITUTED IMIDAZOLES | TPMT, TYMP, PAICS | MITF 1342/4885ALDH1A1 2175/4885AR 4861/4885 |
| US-20140315924-A1 | SULFONIC ACID SALTS OF HETEROCYCLYLAMIDE-SUBSTITUTED IMIDAZOLES | TPMT, MPST, STS | MITF 1425/4885ALDH1A1 1502/4885AR 4651/4885 |
| US-20080004275-A1 | Antiviral 4-Aminocarbonylamino-Substituted Imidazole Compounds | IRF3, EIF2AK2, ZC3HAV1 | MITF 1850/4885ALDH1A1 770/4885AR 4786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.