SCHEMBL15948836

SCHEMBL15948836

O=c1cc(-c2ccc(O)cc2)oc2cc(-c3c(-c4ccc(O)cc4)oc4cc(O)cc(O)c4c3=O)c(O)c(O)c12

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 4/20 0.77
CYP3A4 P08684 8/20 0.70
MAPT P10636 8/20 0.70
KDM4E B2RXH2 7/20 0.70
RECQL P46063 4/20 0.70
BLM P54132 4/20 0.70
PKM P14618 3/20 0.70
APEX1 P27695 3/20 0.70
POLB P06746 3/20 0.70
MIF P14174 2/20 0.70
MCL1 Q07820 2/20 0.70
KMT2A Q03164 10/20 0.65
MEN1 O00255 9/20 0.65
FTO Q9C0B1 7/20 0.65
ALDH1A1 P00352 7/20 0.65
CYP1A1 P04798 6/20 0.65
CYP1B1 Q16678 6/20 0.65
HPGD P15428 6/20 0.65
HSD17B10 Q99714 6/20 0.65
TP53 P04637 6/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17368661 0.95 PTPN1 (0.70) PTPN1CYP3A4MAPTKDM4ERECQL
Taiwaniaflavone SCHEMBL31345923 0.87 PTPN1 (1.00) PTPN1CYP3A4MAPTKDM4ERECQL
Taiwaniaflavone SCHEMBL13980966 0.87 PTPN1 (1.00) PTPN1CYP3A4MAPTKDM4ERECQL
SCHEMBL617814 0.82 PTPN1 (1.00) PTPN1CYP3A4MAPTKDM4ERECQL
SCHEMBL29574181 0.82 PTPN1 (1.00) PTPN1CYP3A4MAPTKDM4ERECQL
SCHEMBL2565483 0.82 CYP3A4 (0.78) PTPN1CYP3A4MAPTKDM4ERECQL
SCHEMBL30684642 0.82 CYP3A4 (0.78) PTPN1CYP3A4MAPTKDM4ERECQL
Kaempferol SCHEMBL17732292 0.81 KMT2A (0.67) PTPN1CYP3A4MAPTKDM4ERECQL
Apigenin SCHEMBL29351464 0.80 KMT2A (1.00) PTPN1CYP3A4MAPTKDM4ERECQL
Apigenin SCHEMBL19428 0.80 KMT2A (1.00) PTPN1CYP3A4MAPTKDM4ERECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11540539-B2 Reduced sodium food products GENERAL MILLS, INC. (US) 2023-01-03 US disclosed
EP-3732994-B1 REDUCED SODIUM FOOD PRODUCTS GEN MILLS INC (US) 2022-11-09 EP disclosed
EP-2954037-B1 REDUCED SODIUM FOOD PRODUCTS GEN MILLS INC (US) 2018-04-11 EP disclosed
US-20150374021-A1 REDUCED SODIUM FOOD PRODUCTS GENERAL MILLS, INC. 2015-12-31 US disclosed
WO-2014124222-A1 REDUCED SODIUM FOOD PRODUCTS GENERAL MILLS, INC. (US) 2014-08-14 WO disclosed