SCHEMBL617814

SCHEMBL617814

O=c1c(-c2c(O)cc(O)c3c(=O)cc(-c4ccc(O)cc4)oc23)c(-c2ccc(O)cc2)oc2cc(O)cc(O)c12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 3/20 1.00
KDM4E B2RXH2 3/20 1.00
CYP3A4 P08684 3/20 1.00
MAPT P10636 3/20 1.00
PKM P14618 2/20 1.00
APEX1 P27695 2/20 1.00
POLB P06746 1/20 1.00
MIF P14174 1/20 1.00
RECQL P46063 1/20 1.00
BLM P54132 1/20 1.00
MCL1 Q07820 1/20 1.00
CDK5 Q00535 3/20 0.71
CDK5R1 Q15078 3/20 0.71
CBS P35520 2/20 0.71
PARP1 P09874 9/20 0.67
PARP2 Q9UGN5 6/20 0.67
APP P05067 5/20 0.62
MEN1 O00255 4/20 0.62
KMT2A Q03164 4/20 0.62
TDP1 Q9NUW8 3/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29574181 1.00 PTPN1 (1.00) PTPN1KDM4ECYP3A4MAPTPKM
SCHEMBL17301661 0.95 KDM4E (0.90) PTPN1KDM4ECYP3A4MAPTPKM
Cupressuflavone SCHEMBL31670258 0.84 CBS (1.00) PTPN1KDM4ECYP3A4MAPTPKM
SCHEMBL2565483 0.84 CYP3A4 (0.78) PTPN1KDM4ECYP3A4MAPTPKM
Cupressuflavone SCHEMBL505213 0.84 CBS (1.00) PTPN1KDM4ECYP3A4MAPTPKM
SCHEMBL30684642 0.84 CYP3A4 (0.78) PTPN1KDM4ECYP3A4MAPTPKM
Cupressuflavone SCHEMBL4650575 0.83 CBS (0.97) PTPN1KDM4ECYP3A4MAPTPKM
SCHEMBL15948836 0.82 PTPN1 (0.77) PTPN1KDM4ECYP3A4MAPTPKM
Agathisflavone SCHEMBL30637380 0.80 CBS (1.00) PTPN1KDM4ECYP3A4MAPTPKM
Agathisflavone SCHEMBL616142 0.80 CBS (1.00) PTPN1KDM4ECYP3A4MAPTPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104274831-A Composition based on naturally derived peptide and inflammation inhibitor and/or anti-oxidation compound SOO TUCK POOI 2015-01-14 CN claimed
CN-103221056-A Electronically Modified Reaction Intermediates MARKOU DEMETRIOS 2013-07-24 CN claimed
EP-2603225-A2 ELECTRONICALLY MODIFIED REACTION INTERMIDEATES Markou, Demetrios (US) 2013-06-19 EP claimed
WO-2012024196-A2 A NOVEL METHOD FOR CREATING, SUSPENDING AND STABILIZING ELECTRONICALLY MODIFIED REACTION INTERMIDEATES MARKOU DEMETRIOS (US) 2012-02-23 WO claimed
US-20120039796-A1 Novel method for creating, suspending and stabilizing electronically modified oxygen derivatives, along with creating, suspending and stabilizing electronically modified reaction intermediates, in a bio compatible fluorocarbon suspension, for the purpose of inducing a cascading immune response in mammalian patients MARKOU DEMETRIOS (US) 2012-02-16 US claimed
CN-101049301-A Pharmaceutical preparation of biflavone compound for anti gout HUIBEI COLLEGE OF CHINESE MEDI (CN) 2007-10-10 CN claimed
US-20020068757-A1 Biflavanoids and derivatives thereof as antiviral agents ADVANCED LIFE SCIENCES, INC. 2002-06-06 US claimed
US-6399654-B1 ADMINISTERING MIXTURE OF VIRICIDE AND BIOFLAVANOID ADVANCED LIFE SCIENCES, INC. 2002-06-04 US claimed
WO-1998046238-A1 BIFLAVINOIDS AND DERIVATIVES THEREOF AS ANTIVIRAL AGENTS, ALONE OR IN COMBINATION WITH AT LEAST ONE KNOWN ANTIVIRAL AGENT MEDICHEM RESEARCH, INC. (US) 1998-10-22 WO claimed
EP-0833631-A1 BIFLAVANOIDS AND DERIVATIVES THEREOF AS ANTIVIRAL AGENTS MEDICHEM RESEARCH, INC. (US) 1998-04-08 EP claimed
WO-1997000679-A1 BIFLAVANOIDS AND DERIVATIVES THEREOF AS ANTIVIRAL AGENTS MEDICHEM RESEARCH, INC. (US) 1997-01-09 WO claimed
EP-4580594-A1 ANTIOXIDANT COMPOSITION COMPRISING 5-DEOXYFLAVONOIDS AnalytiCon Discovery - Zweigniederlassung der BRAIN Biotech AG (DE) 2025-07-09 EP disclosed
US-20240389587-A1 COMPOSITIONS AND METHODS FOR CONTROLLING PHYTOPATHOGENIC INFECTIONS INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT (INRAE) (FR) 2024-11-28 US disclosed
WO-2024046834-A1 ANTIOXIDANT COMPOSITION COMPRISING 5-DEOXYFLAVONOIDS ANALYTICON DISCOVERY GMBH (DE) 2024-03-07 WO disclosed
EP-4331564-A1 ANTIOXIDANT COMPOSITION COMPRISING 5-DEOXYFLAVONOIDS Analyticon Discovery GmbH (DE) 2024-03-06 EP disclosed
US-5773462-A INFLUENZA THERAPY MEDICHEM RESEARCH, INC. (US) 1998-06-30 US disclosed
EP-0833631-A1 BIFLAVANOIDS AND DERIVATIVES THEREOF AS ANTIVIRAL AGENTS MEDICHEM RESEARCH, INC. (US) 1998-04-08 EP disclosed
EP-0833631-A1 BIFLAVANOIDS AND DERIVATIVES THEREOF AS ANTIVIRAL AGENTS MEDICHEM RESEARCH, INC. (US) 1998-04-08 EP disclosed
WO-1997000679-A1 BIFLAVANOIDS AND DERIVATIVES THEREOF AS ANTIVIRAL AGENTS MEDICHEM RESEARCH, INC. (US) 1997-01-09 WO disclosed
WO-1997000679-A1 BIFLAVANOIDS AND DERIVATIVES THEREOF AS ANTIVIRAL AGENTS MEDICHEM RESEARCH, INC. (US) 1997-01-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020068757-A1 Biflavanoids and derivatives thereof as antiviral agents HK2, GYS2, HK1 PTPN1 1427/4885KDM4E 782/4885CYP3A4 533/4885
US-20240389587-A1 COMPOSITIONS AND METHODS FOR CONTROLLING PHYTOPATHOGENIC INFECTIONS XBP1, ERN1, ERN2 PTPN1 2079/4885KDM4E 2982/4885CYP3A4 2585/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.